Non-Primate Monocytes - CD14, CD16 - Ziegler-Heitbrock


Cancer immunosurveillance: role of patrolling monocytes.


Classical inflammatory monocytes and their derivative macrophages promote tumor metastasis whereas CD8(+) T and NK cells restrict tumor growth. In a recent paper published in Science, Hanna and colleagues demonstrate that another monocyte population, nonclassical patrolling monocytes, is enriched in the microvasculature of tumor-challenged lung and reduces tumor metastasis by recruiting NK cells.

Authors: Cassetta L, Pollard JW
Journal: Cell Res.; 2016 Jan; 26(1) 3-4. doi:10.1038/cr.2015.144
Year: 2016
PubMed: PMID: 26634605 (Go to PubMed)