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Literature Mouse Monocytes Subsets

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Title 		Journal
Year 		Abstract
PubMed
AlAsfoor S, Jessen E, Pullapantula SR, Voisin JR, Hsi LC, Pavelko KD, Farwana S, Patraw JA, Chai XY, Ji S, Strausbauch MA, Cipriani G, Wei L, Linden DR, Hou R, Myers R, Bhattarai Y, Wykosky J, Burns AJ, Dasari S, Farrugia G, Grover M,:
Mass Cytometric Analysis of Circulating Monocyte Subsets in a Murine Model of Diabetic Gastroparesis.
Am J Physiol Gastrointest Liver Physiol;2025Feb13. doi:10.1152/ajpgi.00229.2024
2025		 Abstract PubMed
Cavalcanti de Albuquerque JP, Hunter J, Domingues RG, Harno E, Worth AA, Liguori FM, D'Alessio A, Aviello G, Bechtold D, White A, Luckman SM, Hepworth MR, D'Agostino G,:
Brain sensing of metabolic state regulates circulating monocytes.
Sci Immunol;2025Apr04; 10 (106) 3226. doi:10.1126/sciimmunol.adr3226
2025		 Abstract PubMed
Conn MO, DeJong EN, Marko DM, Fayyazi R, Kukje Zada D, Foley KP, Barra NG, Bowdish DME, Schertzer JD.:
Microbiota protect against frailty, loss of skeletal muscle, and maintain inflammatory tone during aging in mice.
Am J Physiol Cell Physiol . 2025 Mar 1;328(3):C887-C894. doi: 10.1152/ajpcell.00869.2024.
2025		 Abstract PubMed
Komaru Y, Ning L, Lama C, Suresh A, Kefaloyianni E, Miller MJ, Kawana S, Shepherd HM, Li W, Kreisel D, Herrlich A,:
Acute kidney injury triggers hypoxemia by lung intravascular neutrophil retention that reduces capillary blood flow.
J Clin Invest;2025Mar06. doi:10.1172/JCI186705
2025		 Abstract PubMed
Pekayvaz K, Kilani B, Joppich M, Eivers L, Brambs S, Knottenberg V, Akgöl S, Yue K, Li L, Martinez-Navarro A, Kaiser R, Meißner N, Schulz H, Belz L, Akhalkatsi A, Stockhausen S, Mueller TT, Millonig S, Hartelt L, Gold C, Janjic A, Polewka V, Wendler F, Dr:
Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis and correlate with thrombus resolution.
Immunity . 2025 Apr 18:S1074-7613(25)00139-6. doi: 10.1016/j.immuni.2025.03.020.
2025		 Abstract PubMed
Roy K, Ghosh S, Karmakar S, Mandal P, Hussain A, Dutta A, Pal C,:
Inverse correlation between Leishmania-induced TLR1/2 and TGF-beta differentially regulates parasite persistence in bone marrow during the chronic phase of infection.
Cytokine; 2025 Jan:185:156811.1 doi:10.1016/j.cyto.2024.156811
2025		 Abstract PubMed
Tan Z, Hall P, Mack M, Snelgrove SL, Kitching AR, Hickey MJ,:
BOTH CLASSICAL AND NON-CLASSICAL MONOCYTES PATROL GLOMERULAR CAPILLARIES AND PROMOTE ACUTE GLOMERULAR INFLAMMATION.
Am J Pathol; 2025 Jan;195(1):89-101 doi:10.1016/j.ajpath.2024.07.010
2025		 Abstract PubMed
Gallerand A, Dolfi B, Stunault MI, Caillot Z, Castiglione A, Strazzulla A, Chen C, Heo GS, Luehmann H, Batoul F, Vaillant N, Dumont A, Pilot T, Merlin J, Zair FN, Gilleron J, Bertola A, Carmeliet P, Williams JW, Arguello RJ, Masson D, Dombrowicz D, Yvan-C:
Glucose metabolism controls monocyte homeostasis and migration but has no impact on atherosclerosis development in mice.
Nat Commun;2024Oct19; 15 (1) 9027. doi:10.1038/s41467-024-53267-5
2024		 Abstract PubMed
Tang D, Liu Y, Duan R, Lin R, Li Z, Liu X, Huang J, Zhao M,:
COL6A6 Peptide Vaccine Alleviates Atherosclerosis through Inducing Immune Response and Regulating Lipid Metabolism in Apoe-/- Mice.
Cells;2024Sep21; 13 (18) . doi:10.3390/cells13181589
2024		 Abstract PubMed
Hayashi Y, Kamimura-Aoyagi Y, Nishikawa S, Noka R, Iwata R, Iwabuchi A, Watanabe Y, Matsunuma N, Yuki K, Kobayashi H, Harada Y, Harada H,:
IL36G-producing neutrophil-like monocytes promote cachexia in cancer.
Nat Commun;2024Sep12; 15 (1) 7662. doi:10.1038/s41467-024-51873-x
2024		 Abstract PubMed
Watanabe H, Rana M, Son M, Chiu PY, Fei-Bloom Y, Choi K, Diamond B, Sherry B,:
Single cell RNA-seq reveals cellular and transcriptional heterogeneity in the splenic CD11b+Ly6Chigh monocyte population expanded in sepsis-surviving mice.
Mol Med;2024Nov06; 30 (1) 202. doi:10.1186/s10020-024-00970-0
2024		 Abstract PubMed
Huynh P, Hoffmann JD, Gerhardt T, Kiss MG, Zuraikat FM, Cohen O, Wolfram C, Yates AG, Leunig A, Heiser M, Gaebel L, Gianeselli M, Goswami S, Khamhoung A, Downey J, Yoon S, Chen Z, Roudko V, Dawson T, Ferreira da Silva J, Ameral NJ, Morgenroth-Rebin J, D'S:
Myocardial infarction augments sleep to limit cardiac inflammation and damage.
Nature;2024Nov; 635 (8037) 168. doi:10.1038/s41586-024-08100-w
2024		 Abstract PubMed
Cruz Tleugabulova M, Melo SP, Wong A, Arlantico A, Liu M, Webster JD, Lau J, Lechner A, Corak B, Hodgins JJ, Garlapati VS, De Simone M, Korin B, Avraham S, Lund J, Jeet S, Reiss A, Bender H, Austin CD, Darmanis S, Modrusan Z, Brightbill H, Durinck S, Diam:
Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade.
Nat Commun;2024Nov06; 15 (1) 9575. doi:10.1038/s41467-024-53700-9
2024		 Abstract PubMed
Liu X, Ren Z, Tan C, Núñez-Santana FL, Kelly ME, Yan Y, Sun H, Abdala-Valencia H, Yang W, Wu Q, Toyoda T, Milisav M, Casalino-Matsuda SM, Lecuona E, Cerier EJ, Heung LJ, Abazeed ME, Perlman H, Gao R, Chandel NS, Budinger GRS, Bharat A,:
Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis.
J Clin Invest;2024Oct01; 134 (22) . doi:10.1172/JCI179527
2024		 Abstract PubMed
Mohamed SH, Vanhoffelen E, Shun Fu M, Hei Lau P, Hain S, Seldeslachts L, Cosway E, Anderson G, McCulloch L, Vande Velde G, Drummond RA,:
CSF1R inhibition by PLX5622 reduces pulmonary fungal infection by depleting MHCIIhi interstitial lung macrophages.
Mucosal Immunol; 2024 Dec;17(6):1256-1272. . doi:10.1016/j.mucimm.2024.08.007
2024		 Abstract PubMed
Stocks H, De Leeuw E, Lambrecht BN, Vandekerckhove L, van Loo G, Wullaert A,:
Development of human innate immune responses in a humanized mouse model expressing four human myelopoiesis transgenes.
Front Immunol;2024; 15 1419117. doi:10.3389/fimmu.2024.1419117
2024		 Abstract PubMed
Medina I, Wieland EB, Temmerman L, Otten JJT, Bermudez B, Bot I, Rademakers T, Wijnands E, Schurgers L, Mees B, van Berkel TJC, Goossens P, Biessen EAL,:
Colony stimulating factor 1 receptor (Csf1r) expressing cell ablation in mafia (macrophage-specific Fas-induced apoptosis) mice alters monocyte landscape and atherosclerotic lesion characteristics.
Eur J Immunol;2024Sep04 2350943. doi:10.1002/eji.202350943
2024		 Abstract PubMed
Wang P, Yang S, Li C, Ma B, Yi M, Chen X, Yu M,:
Sulfotransferase homolog 2 receptors blockade on monocyte subsets along with their inflammatory cytokines for septic lung injury.
Exp Lung Res;2024; 50 (1) 146. doi:10.1080/01902148.2024.2398989
2024		 Abstract PubMed
Thierry GR, Baudon EM, Bijnen M, Bellomo A, Lagueyrie M, Mondor I, Simonnet L, Carrette F, Fenouil R, Keshvari S, Hume DA, Dombrowicz D, Bajenoff M,:
Non-classical monocytes scavenge the growth factor CSF1 from endothelial cells in the peripheral vascular tree to ensure survival and homeostasis.
Immunity;2024Jul27. doi:10.1016/j.immuni.2024.07.005
2024		 Abstract PubMed
Wekema L, Schoenmakers S, Schenkelaars N, Laskewitz A, Liu L, Walters L, Harmsen HJM, Steegers-Theunissen RPM, Faas MM,:
Obesity and diet independently affect maternal immunity, maternal gut microbiota and pregnancy outcome in mice.
Front Immunol;2024; 15 1376583. doi:10.3389/fimmu.2024.1376583
2024		 Abstract PubMed
Jiang R, Lu Z, Wang C, Xiao J, Liu Q, Xu X, Shi J, Shen J, Zhu X, Gong P, Zhuang QX, Shi K, Shi W.:
Beta2 adrenergic receptor-mediated abnormal myelopoiesis drives neuroinflammation in aged patients with traumatic brain injury.
Sci Adv. 2024 Jul 19;10(29):eadp5239. doi: 10.1126/sciadv.adp5239
2024		 Abstract PubMed
Yang J, Wei W, Zhang S, Jiang W,:
Chronic stress influences the macrophage M1-M2 polarization balance through beta-adrenergic signaling in hepatoma mice.
Int Immunopharmacol;2024Sep10; 138 112568. doi:10.1016/j.intimp.2024.112568
2024		 Abstract PubMed
Burgess MO, Janas P, Berry K, Mayr H, Mack M, Jenkins SJ, Bain CC, McSorley HJ, Schwarze J,:
Helminth induced monocytosis conveys protection from respiratory syncytial virus infection in mice.
Allergy;2024Aug; 79 (8) 2157. doi:10.1111/all.16206
2024		 Abstract PubMed
Medina-Ruiz L, Bartolini R, Mathie H, Halawa HA, Cunningham M, Graham GJ,:
CCR1 and CCR2 Coexpression on Monocytes Is Nonredundant and Delineates a Distinct Monocyte Subpopulation.
J Immunol;2024Jul15; 213 (2) 214. doi:10.4049/jimmunol.2400007
2024		 Abstract PubMed
Sommer K, Garibagaoglu H, Paap EM, Wiendl M, Müller TM, Atreya I, Krönke G, Neurath MF, Zundler S,:
Discrepant Phenotyping of Monocytes Based on CX3CR1 and CCR2 Using Fluorescent Reporters and Antibodies.
Cells;2024 May 10;13(10):819 . doi:10.3390/cells13100819
2024		 Abstract PubMed
Yan J, Tie G, Tutto A, Messina LM,:
Hypercholesterolemia impairs collateral artery enlargement by ten-eleven translocation 1-dependent hematopoietic stem cell autonomous mechanism in a murine model of limb ischemia.
JVS Vasc Sci;2024; 5 100203. doi:10.1016/j.jvssci.2024.100203
2024		 Abstract PubMed
Kou T, Kang L, Zhang B, Li J, Zhao B, Zeng W, Hu:
RBP-J regulates homeostasis and function of circulating Ly6Clo monocytes.
Elife. 2024 Feb 26;12:RP88135. doi: 10.7554/eLife.88135
2024		 Abstract PubMed
Gudenschwager Basso EK, Ju J, Soliman E, de Jager C, Wei X, Pridham KJ, Olsen ML, Theus MH:
Immunoregulatory and neutrophil-like monocyte subsets with distinct single-cell transcriptomic signatures emerge following brain injury.
J Neuroinflammation. 2024 Feb 3;21(1):41. doi: 10.1186/s12974-024-03032-8.
2024		 Abstract PubMed
Lu H, Yu X, Hou L, Zhang Y, Li L, Qiao X, Cheng H, Du L, Chen J, Zheng Q, Hou J,:
Analysis of CVC1302-Mediated Enhancement of Monocyte Recruitment in Inducing Immune Responses.
Vaccines (Basel);2024Jan15; 12 (1) . doi:10.3390/vaccines12010086
2024		 Abstract PubMed
Goshima T, Ieguchi K, Onishi N, Shimizu T, Takayanagi D, Watanabe M, Fujimoto Y, Ohkuma R, Suzuki R, Tsurui T, Mura E, Iriguchi N, Ishiguro T, Shimokawa M, Hirasawa Y, Kubota Y, Ariizumi H, Horiike A, Yoshimura K, Tsuji M, Kiuchi Y, Kobayashi S, Fujishiro:
Non-classical Monocytes Enhance the Efficacy of Immune Checkpoint Inhibitors on Colon Cancer in a Syngeneic Mouse Model.
Anticancer Res;2024Jan; 44 (1) 23. doi:10.21873/anticanres.16784
2024		 Abstract PubMed
Kim ID, Ju H, Minkler J, Madkoor A, Park KW, Cho S,:
Obesity-induced Ly6CHigh and Ly6CLow monocyte subset changes abolish post-ischemic limb conditioning benefits in stroke recovery.
J Cereb Blood Flow Metab; 2024 May;44(5):689-701. doi:10.1177/0271678X231215101
2024		 Abstract PubMed
Glorion M, Pascale F, Huriet M, Estephan J, Gouin C, Urien C, Bourge M, Egidy G, Richard C, Gelin V, De Wolf J, Le Guen M, Magnan A, Roux A, Devillier P, Schwartz-Cornil I, Sage E,:
Differential early response of monocyte/macrophage subsets to intra-operative corticosteroid administration in lung transplantation.
Front Immunol;2023; 14 1281546. doi:10.3389/fimmu.2023.1281546
2023		 Abstract PubMed
Kandalla PK, Subburayalu J, Cocita C, de Laval B, Tomasello E, Iacono J, Nitsche J, Canali MM, Cathou W, Bessou G, Mossadegh-Keller N, Huber C, Mouchiroud G, Bourette RP, Grasset MF, Bornhäuser M, Sarrazin S, Dalod M, Sieweke MH,:
M-CSF directs myeloid and NK cell differentiation to protect from CMV after hematopoietic cell transplantation.
EMBO Mol Med;2023Aug28 17694. doi:10.15252/emmm.202317694
2023		 Abstract PubMed
Akbarzadeh R, Czyz C, Thomsen SY, Schilf P, Murthy S, Sadik CD, König P,:
Monocyte populations are involved in the pathogenesis of experimental epidermolysis bullosa acquisita.
Front Immunol;2023; 14 1241461. doi:10.3389/fimmu.2023.1241461
2023		 Abstract PubMed
Gao L, Zhao Y, Wu H, Lin X, Guo F, Li J, Long Y, Zhou B, She J, Zhang C, Sheng J, Jin L, Wu Y, Huang H,:
Polycystic Ovary Syndrome Fuels Cardiovascular Inflammation and Aggravates Ischemic Cardiac Injury.
Circulation;2023 Dec 12;148(24):1958-1973 doi:10.1161/CIRCULATIONAHA.123.065827
2023		 Abstract PubMed
Droho S, Voigt AP, Sterling JK, Rajesh A, Chan KS, Cuda CM, Perlman H, Lavine JA,:
NR4A1 deletion promotes pro-angiogenic polarization of macrophages derived from classical monocytes in a mouse model of neovascular age-related macular degeneration.
J Neuroinflammation;2023Oct19; 20 (1) 238. doi:10.1186/s12974-023-02928-1
2023		 Abstract PubMed
Yang L, Gao Q, Li Q, Guo S,:
PD-L1 Blockade Improves Survival in Sepsis by Reversing Monocyte Dysfunction and Immune Disorder.
Inflammation;2024 Feb;47(1):114-128 doi:10.1007/s10753-023-01897-0
2023		 Abstract PubMed
Kapanadze T, Gamrekelashvili J, Sablotny S, Schroth FN, Xu Y, Chen R, Rong S, Shushakova N, Gueler F, Haller H, Limbourg FP,:
Validation of CSF-1 receptor (CD115) staining for analysis of murine monocytes by flow cytometry.
J Leukoc Biol; 2024 Feb 23;115(3):573-582 doi:10.1093/jleuko/qiad147
2023		 Abstract PubMed
Janssen H, Kahles F, Liu D, Downey J, Koekkoek LL, Roudko V, D'Souza D, McAlpine CS, Halle L, Poller WC, Chan CT, He S, Mindur JE, Kiss MG, Singh S, Anzai A, Iwamoto Y, Kohler RH, Chetal K, Sadreyev RI, Weissleder R, Kim-Schulze S, Merad M, Nahrendorf M, :
Monocytes re-enter the bone marrow during fasting and alter the host response to infection.
Immunity;2023 Apr 11;56(4):783-796.e7 doi:10.1016/j.immuni.2023.01.024
2023		 Abstract PubMed
Zhou HY, Feng X, Wang LW, Zhou R, Sun H, Chen X, Lu RB, Huang Y, Guo Q, Luo XH,:
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain.
Cell Metab;2023Sep07. doi:10.1016/j.cmet.2023.08.009
2023		 Abstract PubMed
Kare AJ, Nichols L, Zermeno R, Raie MN, Tumbale SK, Ferrara KW,:
OMIP-095: 40-Color spectral flow cytometry delineates all major leukocyte populations in murine lymphoid tissues.
Cytometry A;2023Sep28. doi:10.1002/cyto.a.24788
2023		 Abstract PubMed
Miyagawa F, Ozato K, Tagaya Y, Asada H,:
Type I Interferon derived from Ly6Chi monocytes suppresses type 2 inflammation in murine model of atopic dermatitis.
J Invest Dermatol;2023Sep20. doi:10.1016/j.jid.2023.08.022
2023		 Abstract PubMed
He S, Liu J, Xue Y, Fu T, Li Z,:
Sympathetic Nerves Coordinate Corneal Epithelial Wound Healing by Controlling the Mobilization of Ly6Chi Monocytes From the Spleen to the Injured Cornea.
Invest Ophthalmol Vis Sci;2023Sep01; 64 (12) 13. doi:10.1167/iovs.64.12.13
2023		 Abstract PubMed
O'Connor KW, Liu T, Kim S, Briseño CG, Georgopoulos K, Murphy TL, Murphy KM,:
Bcl6, Irf2, and Notch2 promote nonclassical monocyte development.
Proc Natl Acad Sci U S A;2023Aug29; 120 (35) 2220853120. doi:10.1073/pnas.2220853120
2023		 Abstract PubMed
Almamoun R, Pierozan P, Manoharan L, Karlsson O,:
Altered gut microbiota community structure and correlated immune system changes in dibutyl phthalate exposed mice.
Ecotoxicol Environ Saf;2023Aug05; 262 115321. doi:10.1016/j.ecoenv.2023.115321
2023		 Abstract PubMed
Zhang L, Peng X, Wang Q, Li J, Lv S, Han S, Zhang L, Ding H, Wang CY, Xiao G, Du X, Peng K, Li H, Liu W,:
CCR2 is a host entry receptor for severe fever with thrombocytopenia syndrome virus.
Sci Adv;2023Aug02; 9 (31) 6856. doi:10.1126/sciadv.adg6856
2023		 Abstract PubMed
Liu Y, Su S, Shayo S, Bao W, Pal M, Dou K, Shi PA, Aygun B, Campbell-Lee S, Lobo CA, Mendelson A, An X, Manwani D, Zhong H, Yazdanbakhsh K,:
Hemolysis dictates monocyte differentiation via two distinct pathways in sickle cell disease vaso-occlusion.
J Clin Invest . 2023 Sep 15;133(18):e172087. doi: 10.1172/JCI172087.
2023		 Abstract PubMed
Bai X, Zhou B, Wu S, Zhang X, Zuo X, Li T,:
GTS-21 alleviates murine collagen-induced arthritis through inhibition of peripheral monocyte trafficking into the synovium.
Int Immunopharmacol;2023Jul21; 122 110676. doi:10.1016/j.intimp.2023.110676
2023		 Abstract PubMed
Xu Q, Chen J, Ye W, Zhang C, Wang D, Wei W, Hu S,:
Activation of angiotensin II type 2 receptor attenuates lung injury of collagen-induced arthritis by alleviating endothelial cell injury and promoting Ly6Clo monocyte transition.
Eur J Pharmacol. 2023 Feb 15;941:175466. doi: 10.1016/j.ejphar.2022.175466. Epub 2022 Dec 14
2023		 Abstract PubMed
Padgett LE, Marcovecchio PM, Olingy CE, Araujo DJ, Steel K, Dinh HQ, Alimadadi A, Zhu YP, Meyer MA, Kiosses WB, Thomas GD, Hedrick CC,:
Nonclassical monocytes potentiate anti-tumoral CD8+ T cell responses in the lungs.
Front Immunol;2023; 14 1101497. doi:10.3389/fimmu.2023.1101497
2023		 Abstract PubMed
Lecordier S, Menet R, Allain AS, ElAli A,:
Non-classical monocytes promote neurovascular repair in cerebral small vessel disease associated with microinfarctions via CX3CR1.
J Cereb Blood Flow Metab;2023Jun21 271678. doi:10.1177/0271678X231183742
2023		 Abstract PubMed
Montgomery AB, Chen SY, Wang Y, Gadhvi G, Mayr MG, Cuda CM, Dominguez S, Moradeke Makinde HK, Gurra MG, Misharin AV, Mandelin AM, Ruderman EM, Thakrar A, Brar S, Carns M, Aren K, Akbarpour M, Filer A, Nayar S, Teososio A, Major T, Bharat A, Budinger GRS, :
Tissue-resident, extravascular Ly6c- monocytes are critical for inflammation in the synovium.
Cell Rep;2023May18; 42 (5) 112513. doi:10.1016/j.celrep.2023.112513
2023		 Abstract PubMed
Rhee C, Scadden EW, Wong LP, Schiroli G, Mazzola MC, Chea PL, Kato H, Hoyer FF, Mistry M, Lee BK, Kim J, Nahrendorf M, Mansour M, Sykes DB, Sadreyev R, Scadden DT,:
Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors.
Blood . 2023 Aug 17;142(7):658-674. doi: 10.1182/blood.2023020257.
2023		 Abstract PubMed
Tadepalli S, Clements DR, Saravanan S, Arroyo Hornero R, Lüdtke A, Blackmore B, Paulo JA, Gottfried-Blackmore A, Seong D, Park S, Chan L, Kopecky BJ, Liu Z, Ginhoux F, Lavine KJ, Murphy JP, Mack M, Graves EE, Idoyaga J,:
Rapid recruitment and IFN-I-mediated activation of monocytes dictate focal radiotherapy efficacy.
Sci Immunol;2023Jun02; 8 (84) 7446. doi:10.1126/sciimmunol.add7446
2023		 Abstract PubMed
Byrnes D, Masterson CH, Brady J, Alagesan S, Gonzalez HE, McCarthy SD, Fandiño J, O'Toole DP, Laffey JG,:
Differential Effects of Cytokine Versus Hypoxic Preconditioning of Human Mesenchymal Stromal Cells in Pulmonary Sepsis Induced by Antimicrobial-Resistant Klebsiella pneumoniae.
Pharmaceuticals (Basel);2023Jan19; 16 (2) . doi:10.3390/ph16020149
2023		 Abstract PubMed
Loinard C, Benadjaoud MA, Lhomme B, Flamant S, Baijer J, Tamarat R,:
Inflammatory cells dynamics control neovascularization and tissue healing after localized radiation induced injury in mice.
Commun Biol;2023May29; 6 (1) 571. doi:10.1038/s42003-023-04939-3
2023		 Abstract PubMed
Brandi J, Wiethe C, Riehn M, Jacobs T.:
OMIP-93: A 41-color high parameter panel to characterize various co-inhibitory molecules and their ligands in the lymphoid and myeloid compartment in mice.
Cytometry A . 2023 Aug;103(8):624-630. doi: 10.1002/cyto.a.24740. E
2023		 Abstract PubMed
van Olst L, Kamermans A, van der Pol SMA, Rodríguez E, Hulshof LA, van Dijk RE, Vonk DN, Schouten M, Witte ME, de Vries HE, Middeldorp J,:
Age-associated systemic factors change central and peripheral immunity in adult male mice.
Brain Behav Immun;2023May09. doi:10.1016/j.bbi.2023.05.004
2023		 Abstract PubMed
Ma W, Oliveira-Nunes MC, Xu K, Kossenkov A, Reiner BC, Crist RC, Hayden J, Chen Q,:
Type I interferon response in astrocytes promotes brain metastasis by enhancing monocytic myeloid cell recruitment.
Nat Commun;2023May06; 14 (1) 2632. doi:10.1038/s41467-023-38252-8
2023		 Abstract PubMed
Giordano KR, Saber M, Green TRF, Rojas-Valencia LM, Ortiz JB, Murphy SM, Lifshitz J, Rowe RK,:
Colony-Stimulating Factor-1 Receptor Inhibition Transiently Attenuated the Peripheral Immune Response to Experimental Traumatic Brain Injury.
Neurotrauma Rep;2023; 4 (1) 284. doi:10.1089/neur.2022.0092
2023		 Abstract PubMed
Giordano KR, Saber M, Green TRF, Rojas-Valencia LM, Ortiz JB, Murphy SM, Lifshitz J, Rowe RK,:
Colony-Stimulating Factor-1 Receptor Inhibition Transiently Attenuated the Peripheral Immune Response to Experimental Traumatic Brain Injury.
Neurotrauma Rep;2023; 4 (1) 284. doi:10.1089/neur.2022.0092
2023		 Abstract PubMed
Pierozan P, Källsten L, Theodoropoulou E, Almamoun R, Karlsson O,:
Persistent immunosuppressive effects of dibutyl phthalate exposure in adult male mice.
Sci Total Environ; 2023 Mar 11;878:162741 doi:10.1016/j.scitotenv.2023.162741
2023		 Abstract PubMed
Cheng HS, Zhuang R, Pérez-Cremades D, Chen J, Jamaiyar A, Wu W, Sausen G, Tzani A, Plutzky J, Henao-Mejia J, Goodney PP, Creager MA, Sabatine MS, Bonaca MP, Feinberg MW,:
A miRNA-CXCR4 signaling axis impairs monopoiesis and angiogenesis in diabetic critical limb ischemia.
JCI Insight; 2023 Apr 10;8(7):e163360. doi:10.1172/jci.insight.163360
2023		 Abstract PubMed
Zhang J, Hao W, Zhang J, Li T, Ma Y, Wang Y, Li X, Cui W, Du J,:
CXCL16 Promotes Ly6Chigh Monocyte Infiltration and Impairs Heart Function after Acute Myocardial Infarction.
J Immunol;2023Mar15; 210 (6) 820. doi:10.4049/jimmunol.2200249
2023		 Abstract PubMed
Saadane A, Veenstra AA, Minns MS, Tang J, Du Y, Abubakr Elghazali F, Lessieur EM, Pearlman E, Kern TS,:
CCR2-positive monocytes contribute to the pathogenesis of early diabetic retinopathy in mice.
Diabetologia;2023 Mar;66(3):590-602. doi:10.1007/s00125-022-05860-w
2023		 Abstract PubMed
Heidbreder K, Sommer K, Wiendl M, Müller TM, Atreya I, Hildner K, Neurath MF, Zundler S,:
Nr4a1-dependent non-classical monocytes are important for macrophage-mediated wound healing in the large intestine.
Front Immunol;2023 Jan 18;13:1040775 doi:10.3389/fimmu.2022.1040775
2023		 Abstract PubMed
Ghareghani M, Pons V, Laflamme N, Zibara K, Rivest S,:
Inhibiting nighttime melatonin and boosting cortisol increase patrolling monocytes, phagocytosis, and myelination in a murine model of multiple sclerosis.
Exp Mol Med;2023 Jan;55(1):215-227 doi:10.1038/s12276-023-00925-1
2023		 Abstract PubMed
Rumianek AN, Davies B, Channon KM, Greaves DR, Purvis GSD,:
A Human CD68 Promoter-Driven Inducible Cre-Recombinase Mouse Line Allows Specific Targeting of Tissue Resident Macrophages.
Front Immunol;2022; 13 918636. doi:10.3389/fimmu.2022.918636
2022		 Abstract PubMed
Rumianek AN, Davies B, Channon KM, Greaves DR, Purvis GSD,:
A Human CD68 Promoter-Driven Inducible Cre-Recombinase Mouse Line Allows Specific Targeting of Tissue Resident Macrophages.
Front Immunol;2022; 13 918636. doi:10.3389/fimmu.2022.918636
2022		 Abstract PubMed
Emoto T, Lu J, Sivasubramaniyam T, Maan H, Khan AB, Abow AA, Schroer SA, Hyduk SJ, Althagafi MG, McKee TD, Fu F, Shabro S, Ulndreaj A, Chiu F, Paneda E, Pacheco S, Wang T, Li A, Jiang JX, Libby P, Husain M, Wang B, Rubin BB, Cybulsky MI, Robbins CS,:
Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche.
Immunity;2022May10; 55 (5) 862-878. doi:10.1016/j.immuni.2022.04.005
2022		 Abstract PubMed
Tran T, Lavillegrand JR, Lereverend C, Esposito B, Cartier L, Montabord M, Tran-Rajau J, Diedisheim M, Gruel N, Ouguerram K, Paolini L, Lenoir O, Pinteaux E, Brabencova E, Tanchot C, Urquia P, Lehmann-Che J, Le Naour R, Merrouche Y, Stockmann C, Mallat Z,:
Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6Chi monocytes and differentiation to pro-angiogenic myeloid cells.
Nat Commun;2022Sep14; 13 (1) 5399. doi:10.1038/s41467-022-33034-0
2022		 Abstract PubMed
Tran T, Lavillegrand JR, Lereverend C, Esposito B, Cartier L, Montabord M, Tran-Rajau J, Diedisheim M, Gruel N, Ouguerram K, Paolini L, Lenoir O, Pinteaux E, Brabencova E, Tanchot C, Urquia P, Lehmann-Che J, Le Naour R, Merrouche Y, Stockmann C, Mallat Z,:
Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6Chi monocytes and differentiation to pro-angiogenic myeloid cells.
Nat Commun;2022Sep14; 13 (1) 5399. doi:10.1038/s41467-022-33034-0
2022		 Abstract PubMed
Liu P, Gao Y, Luo P, Yu H, Guo S, Liu F, Gao J, Xu J, Wang S, Zhang C,:
Glucocorticoid-induced expansion of classical monocytes contributes to bone loss.
Exp Mol Med; 2022 Jun;54(6):765-776. . doi:10.1038/s12276-022-00764-6
2022		 Abstract PubMed
Frentzel S, Jeron A, Pausder A, Kershaw O, Volckmar J, Schmitz I, Bruder D,:
IkappaBNS-deficiency protects mice from fatal Listeria monocytogenes infection by blunting pro-inflammatory signature in Ly6Chigh monocytes and preventing exaggerated innate immune responses.
Front Immunol; 2022 Dec 22;13:1028789. doi:10.3389/fimmu.2022.1028789
2022		 Abstract PubMed
Nomura A, Mizuno M, Noto D, Aoyama A, Kuga T, Murayama G, Chiba A, Miyake S,:
Different Spatial and Temporal Roles of Monocytes and Monocyte-Derived Cells in the Pathogenesis of an Imiquimod Induced Lupus Model.
Front Immunol;2022; 13 764557. doi:10.3389/fimmu.2022.764557
2022		 Abstract PubMed
Ren K, Li S, Liang S, Fan F, Lu J, Wei T, Cao X, Gong L, Li H, Zhao J, Qin H, Guo J,:
Notch signaling dependent monocyte conversion alleviates immune-mediated neuropathies by regulating RBP-J/NR4A1 axis.
J Autoimmun; 2022 Dec;133:102945. doi:10.1016/j.jaut.2022.102945
2022		 Abstract PubMed
Rousselle A, Sonnemann J, Amann K, Mildner A, Lodka D, Kling L, Bieringer M, Schneider U, Leutz A, Enghard P, Kettritz R, Schreiber A,:
CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
Ann Rheum Dis;2022 Aug;81(8):1162-1172. . doi:10.1136/annrheumdis-2021-221984
2022		 Abstract PubMed
Manta CP, Leibing T, Friedrich M, Nolte H, Adrian M, Schledzewski K, Krzistetzko J, Kirkamm C, David Schmid C, Xi Y, Stojanovic A, Tonack S, de la Torre C, Hammad S, Offermanns S, Krüger M, Cerwenka A, Platten M, Goerdt S, Géraud C,:
Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression.
Circulation;2022 Dec 6;146(23):1783-1799 doi:10.1161/CIRCULATIONAHA.121.058615
2022		 Abstract PubMed
Xiang Y, Liang B, Zhang X, Qiu X, Deng Q, Yu L, Yu H, Lu Z, Zheng F,:
Atheroprotective mechanism by which folic acid regulates monocyte subsets and function through DNA methylation.
Clin Epigenetics;2022 Feb 28;14(1):32. doi:10.1186/s13148-022-01248-0
2022		 Abstract PubMed
Royo J, Camara A, Bertrand B, Batigne P, Coste A, Pipy B, Aubouy A, NeuroCM Group,:
Kinetics of monocyte subpopulations during experimental cerebral malaria and its resolution in a model of late chloroquine treatment.
Front Cell Infect Microbiol; 2022 Oct 14;12:952993 doi:10.3389/fcimb.2022.952993
2022		 Abstract PubMed
Liu P, Gao Y, Luo P, Yu H, Guo S, Liu F, Gao J, Xu J, Wang S, Zhang C,:
Glucocorticoid-induced expansion of classical monocytes contributes to bone loss.
Exp Mol Med; 2022 Jun;54(6):765-776 doi:10.1038/s12276-022-00764-6
2022		 Abstract PubMed
Wang R, Bao W, Pal M, Liu Y, Yazdanbakhsh K, Zhong H,:
Intermediate monocytes induced by IFN-gamma inhibit cancer metastasis by promoting NK cell activation through FOXO1 and interleukin-27.
J Immunother Cancer; 2022 Jan;10(1):e003539 . doi:10.1136/jitc-2021-003539
2022		 Abstract PubMed
Barman PK, Shin JE, Lewis SA, Kang S, Wu D, Wang Y, Yang X, Nagarkatti PS, Nagarkatti M, Messaoudi I, Benayoun BA, Goodridge HS,:
Production of MHCII-expressing classical monocytes increases during aging in mice and humans.
Aging Cell; 2022 Oct;21(10):e13701. doi:10.1111/acel.13701
2022		 Abstract PubMed
Maquet C, Baiwir J, Loos P, Rodriguez-Rodriguez L, Javaux J, Sandor R, Perin F, Fallon PG, Mack M, Cataldo D, Gillet L, Machiels B,:
Ly6Chi monocytes balance regulatory and cytotoxic CD4 T cell responses to control virus-induced immunopathology.
Sci Immunol;2022Jul15; 7 (73) 3240. doi:10.1126/sciimmunol.abn3240
2022		 Abstract PubMed
Li B, Qi X, Liu Y, Yan Y, Shan J, Cai X, Lv J, Zhou X, Yu T, Ma X,:
Monocyte-derived macrophages: The supplements of hepatic macrophage in Echinococcus multilocularis infected mice.
Immun Inflamm Dis;2022Oct; 10 (10) e699. doi:10.1002/iid3.699
2022		 Abstract PubMed
Ahamed W, Yu RMC, Pan Y, Iwata T, Barathi VA, Wey YS, Tun SBB, Qiu B, Tan A, Wang X, Cheung CMG, Wong TY, Yanagi Y,:
HTRA1 Regulates Subclinical Inflammation and Activates Proangiogenic Response in the Retina and Choroid.
Int J Mol Sci; 2022 Sep 6;23(18):10206. doi:10.3390/ijms231810206
2022		 Abstract PubMed
Mohamedaly S, Levy CS, Korsholm C, Alkhani A, Rosenberg K, Ashouri JF, Nijagal A,:
Hepatic Ly6CLo Non-Classical Monocytes Have Increased Nr4a1 (Nur77) in Murine Biliary Atresia.
J Clin Med; 2022 Sep 8;11(18):5290.) . doi:10.3390/jcm11185290
2022		 Abstract PubMed
Tran T, Lavillegrand JR, Lereverend C, Esposito B, Cartier L, Montabord M, Tran-Rajau J, Diedisheim M, Gruel N, Ouguerram K, Paolini L, Lenoir O, Pinteaux E, Brabencova E, Tanchot C, Urquia P, Lehmann-Che J, Le Naour R, Merrouche Y, Stockmann C, Mallat Z,:
Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6Chi monocytes and differentiation to pro-angiogenic myeloid cells.
Nat Commun;2022 Sep14; 13 (1) 5399. doi:10.1038/s41467-022-33034-0
2022		 Abstract PubMed
Emoto T, Lu J, Sivasubramaniyam T, Maan H, Khan AB, Abow AA, Schroer SA, Hyduk SJ, Althagafi MG, McKee TD, Fu F, Shabro S, Ulndreaj A, Chiu F, Paneda E, Pacheco S, Wang T, Li A, Jiang JX, Libby P, Husain M, Wang B, Rubin BB, Cybulsky MI, Robbins CS,:
Colony stimulating factor-1 producing endothelial cells and mesenchymal stromal cells maintain monocytes within a perivascular bone marrow niche.
Immunity;2022May10; 55 (5) 862-878. doi:10.1016/j.immuni.2022.04.005
2022		 Abstract PubMed
Bettke JA, Tam JW, Montoya V, Butler BP, van der Velden AWM,:
Inflammatory Monocytes Promote Granuloma-Mediated Control of Persistent Salmonella Infection.
Infect Immun 2022 Apr 21;90(4):e0007022. doi:10.1128/iai.00070-22
2022		 Abstract PubMed
Han S, Zhuang H, Arja RD, Reeves WH,:
A novel monocyte differentiation pattern in pristane-induced lupus with diffuse alveolar hemorrhage.
Elife; 2022 Oct 20;11:e76205. doi:10.7554/eLife.76205
2022		 Abstract PubMed
Han S, Zhuang H, Arja RD, Reeves WH,:
A novel monocyte differentiation pattern in pristane-induced lupus with diffuse alveolar hemorrhage.
Elife; 2022 Oct 20;11:e76205. doi:10.7554/eLife.76205
2022		 Abstract PubMed
Wang R, Bao W, Pal M, Liu Y, Yazdanbakhsh K, Zhong H,:
Intermediate monocytes induced by IFN-gamma inhibit cancer metastasis by promoting NK cell activation through FOXO1 and interleukin-27.
J Immunother Cancer; 2022;10:e003539. doi:10.1136/jitc-2021-003539
2022		 Abstract PubMed
Li YH, Zhang Y, Pan G, Xiang LX, Luo DC, Shao JZ,:
Occurrences and Functions of Ly6Chi and Ly6Clo Macrophages in Health and Disease.
Front Immunol;2022; 13 901672. doi:10.3389/fimmu.2022.901672
2022		 Abstract PubMed
Kowalski EA, Soliman E, Kelly C, Gudenschwager Basso EK, Leonard J, Pridham KJ, Ju J, Cash AM, Hazy A, de Jager C, Kaloss AM, Ding H, Hernandez RD, Coleman GM, Wang X, Olsen ML, Pickrell AM, Theus MH,:
Monocyte pro-inflammatory phenotypic control by Ephrin type-A receptor 4 mediates neural tissue damage.
JCI Insight;2022J 7(15):e156319 doi:10.1172/jci.insight.156319
2022		 Abstract PubMed
Deng M, Su D, Xiao N, Zhang Z, Wang Y, Zong F, Li S, Wang J, Zhou D, Zhao Y, Yang H,:
Gdf15 deletion exacerbates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice.
Toxicology;2022 Volume 469, 15 March 2022, 153135 doi:10.1016/j.tox.2022.153135
2022		 Abstract PubMed
Querrey M, Chiu S, Lecuona E, Wu Q, Sun H, Anderson M, Kelly M, Ravi S, Misharin AV, Kreisel D, Bharat A, Budinger GRS,:
CD11b suppresses TLR activation of nonclassical monocytes to reduce primary graft dysfunction after lung transplantation.
J Clin Invest;2022Jul15; 132 (14) e157262 . doi:10.1172/JCI157262
2022		 Abstract PubMed
Kamio N, Yokota A, Tokuda Y, Ogasawara C, Nakano M, Nagao M, Tashiro K, Maekawa T, Onai N, Hirai H,:
A Novel CD135+ Subset of Mouse Monocytes with a Distinct Differentiation Pathway and Antigen-Presenting Properties.
J Immunol;2022Aug01; 209 (3) 498-509. doi:10.4049/jimmunol.2100024
2022		 Abstract PubMed
Rousselle A, Sonnemann J, Amann K, Mildner A, Lodka D, Kling L, Bieringer M, Schneider U, Leutz A, Enghard P, Kettritz R, Schreiber A,:
CSF2-dependent monocyte education in the pathogenesis of ANCA-induced glomerulonephritis.
Ann Rheum Dis;2022Apr13. doi:10.1136/annrheumdis-2021-221984
2022		 Abstract PubMed
Li J, Zhao F, Qin Q, Yang L, Jiang Y, Hou Y, Wang Y, Zhou W, Fang L, Chen L,:
The Effect of CD226 on the Balance between Inflammatory Monocytes and Small Peritoneal Macrophages in Mouse Ulcerative Colitis.
Immunol Invest;2022Apr25 1-10. doi:10.1080/08820139.2022.2065921
2022		 Abstract PubMed
Mirchandani AS, Jenkins SJ, Bain CC, Sanchez-Garcia MA, Lawson H, Coelho P, Murphy F, Griffith DM, Zhang A, Morrison T, Ly T, Arienti S, Sadiku P, Watts ER, Dickinson RS, Reyes L, Cooper G, Clark S, Lewis D, Kelly V, Spanos C, Musgrave KM, Delaney L, Harp:
Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation.
Nat Immunol;2022May27. doi:10.1038/s41590-022-01216-z
2022		 Abstract PubMed
Evren E, Ringqvist E, Doisne JM, Thaller A, Sleiers N, Flavell RA, Di Santo JP, Willinger T,:
CD116+ fetal precursors migrate to the perinatal lung and give rise to human alveolar macrophages.
J Exp Med;2022Feb07; 219 (2) . doi:10.1084/jem.20210987
2022		 Abstract PubMed
Li Q, Xiang G, Peng S, Ji W,:
Temporal and Spatial Characterization of Mononuclear Phagocytes in Circulating, Pulmonary Alveolar, and Interstitial Compartments in LPS-Induced Acute Lung Injury.
Front Surg;2022; 9 837177. doi:10.3389/fsurg.2022.837177
2022		 Abstract PubMed
Yang N, Luna JM, Dai P, Wang Y, Rice CM, Deng L,:
Lung type II alveolar epithelial cells collaborate with CCR2+ inflammatory monocytes in host defense against poxvirus infection.
Nat Commun;2022Mar29; 13 (1) 1671. doi:10.1038/s41467-022-29308-2
2022		 Abstract PubMed
Zhou W, Jiang X, Tang Q, Ding L, Xiao W, Li J, Wu Y, Ruan HB, Shen Z, Chen W,:
Glucosamine facilitates cardiac ischemic recovery via recruiting Ly6Clow monocytes in a STAT1 and O-GlcNAcylation-dependent fashion.
Clin Transl Med;2022Mar; 12 (3) 762. doi:10.1002/ctm2.762
2022		 Abstract PubMed
Lin CM, Huang TH, Chi MC, Guo SE, Lee CW, Hwang SL, Shi CS,:
N-acetylcysteine alleviates fine particulate matter (PM2.5)-induced lung injury by attenuation of ROS-mediated recruitment of neutrophils and Ly6Chigh monocytes and lung inflammation.
Ecotoxicol Environ Saf;2022May17; 239 113632. doi:10.1016/j.ecoenv.2022.113632
2022		 Abstract PubMed
Lehmann ML, Samuels JD, Kigar SL, Poffenberger CN, Lotstein ML, Herkenham M,:
CCR2 monocytes repair cerebrovascular damage caused by chronic social defeat stress.
Brain Behav Immun;2022 Mar;101:346-358.. doi:10.1016/j.bbi.2022.01.011
2022		 Abstract PubMed
Glab JA, Puthalakath H, Zhang SR, Vinh A, Drummond GR, Sobey CG, De Silva TM, Kim HA,:
Bim Deletion Reduces Functional Deficits Following Ischemic Stroke in Association with Modulation of Apoptosis and Inflammation.
Neuromolecular Med;2022Feb11. doi:10.1007/s12017-022-08703-4
2022		 Abstract PubMed
Robinson A, Burgess M, Webb S, Louwe PA, Ouyang Z, Skola D, Han CZ, Batada NN, González-Huici V, Cassetta L, Glass CK, Jenkins SJ, Pollard JW,:
Systemic Influences of Mammary Cancer on Monocytes in Mice.
Cancers (Basel);2022Feb07; 14 (3) . doi:10.3390/cancers14030833
2022		 Abstract PubMed
Teh YC, Chooi MY, Liu D, Kwok I, Lai GC, Ayub Ow Yong L, Ng M, Li JLY, Tan Y, Evrard M, Tan L, Liong KH, Leong K, Goh CC, Chan AYJ, Shadan NB, Mantri CK, Hwang YY, Cheng H, Cheng T, Yu W, Tey HL, Larbi A, St John A, Angeli V, Ruedl C, Lee B, Ginhoux F, Ch:
Transitional premonocytes emerge in the periphery for host defense against bacterial infections.
Sci Adv;2022Mar04; 8 (9) 4641. doi:10.1126/sciadv.abj4641
2022		 Abstract PubMed
Hoffman D, Tevet Y, Trzebanski S, Rosenberg G, Vainman L, Solomon A, Hen-Avivi S, Ben-Moshe NB, Avraham R,:
A non-classical monocyte-derived macrophage subset provides a splenic replication niche for intracellular Salmonella.
Immunity;2021Dec14; 54 (12) 2712-2723. doi:10.1016/j.immuni.2021.10.015
2021		 Abstract PubMed
Li YT, Yamazaki S, Takaki E, Ouchi Y, Kitayama T, Tamai K,:
PDGFRalpha-lineage origin directs monocytes to trafficking proficiency to support peripheral immunity.
Eur J Immunol;2022 Feb;52(2):204-221. doi:10.1002/eji.202149479
2021		 Abstract PubMed
Purvis GSD, Aranda-Tavio H, Channon KM, Greaves DR,:
Bruton's tyrosine kinase (BTK) regulates myeloid cell recruitment during acute inflammation.
Br J Pharmacol;2021Dec12. doi:10.1111/bph.15778
2021		 Abstract PubMed
Shahneh F, Christian Probst H, Wiesmann SC, A-Gonzalez N, Ruf W, Steinbrink K, Raker VK, Becker C,:
Inflammatory Monocyte Counts Determine Venous Blood Clot Formation and Resolution.
Arterioscler Thromb Vasc Biol;2022 Feb;42(2):145-155 doi:10.1161/ATVBAHA.121.317176
2021		 Abstract PubMed
Gärtner F, Gihring A, Roth A, Bischof J, Xu P, Elad L, Wabitsch M, Burster T, Knippschild U,:
Obesity Prolongs the Inflammatory Response in Mice After Severe Trauma and Attenuates the Splenic Response to the Inflammatory Reflex.
Front Immunol;2021; 12 745132. doi:10.3389/fimmu.2021.745132
2021		 Abstract PubMed
Yang P, Wu Q, Sun L, Fang P, Liu L, Ji Y, Park JY, Qin X, Yang X, Wang H,:
Adaptive Immune Response Signaling Is Suppressed in Ly6Chigh Monocyte but Upregulated in Monocyte Subsets of ApoE -/- Mice - Functional Implication in Atherosclerosis.
Front Immunol;2021; 12 809208. doi:10.3389/fimmu.2021.809208
2021		 Abstract PubMed
Kurihara C, Lecuona E, Wu Q, Yang W, Núñez-Santana FL, Akbarpour M, Liu X, Ren Z, Li W, Querrey M, Ravi S, Anderson ML, Cerier E, Sun H, Kelly ME, Abdala-Valencia H, Shilatifard A, Mohanakumar T, Budinger GRS, Kreisel D, Bharat A,:
Crosstalk between nonclassical monocytes and alveolar macrophages mediates transplant ischemia-reperfusion injury through classical monocyte recruitment.
JCI Insight; 2021 Mar 22;6(6):e14728 . doi:10.1172/jci.insight.147282
2021		 Abstract PubMed
Manohar M, Jones EK, Rubin SJS, Subrahmanyam PB, Swaminathan G, Mikhail D, Bai L, Singh G, Wei Y, Sharma V, Siebert JC, Maecker HT, Husain SZ, Park WG, Pandol SJ, Habtezion A,:
Novel Circulating and Tissue Monocytes as Well as Macrophages in Pancreatitis and Recovery.
Gastroenterology;2021; 161 (6) 2014-2029. doi:10.1053/j.gastro.2021.08.033
2021		 Abstract PubMed
Shibuya T, Kamiyama A, Sawada H, Kikuchi K, Maruyama M, Sawado R, Ikeda N, Asano K, Kurotaki D, Tamura T, Yoneda A, Imada K, Satoh T, Akira S, Tanaka M, Yotsumoto S,:
Immunoregulatory Monocyte Subset Promotes Metastasis Associated With Therapeutic Intervention for Primary Tumor.
Front Immunol;2021; 12 663115. doi:10.3389/fimmu.2021.663115
2021		 Abstract PubMed
Kaur K, Bachus H, Lewis C, Papillion AM, Rosenberg AF, Ballesteros-Tato A, León B,:
GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation.
Cell Rep;2021Dec28; 37 (13) 110178. doi:10.1016/j.celrep.2021.110178
2021		 Abstract PubMed
Utomo L, Fahy N, Kops N, van Tiel ST, Waarsing J, Verhaar JAN, Leenen PJM, van Osch GJVM, Bastiaansen-Jenniskens YM,:
Macrophage phenotypes and monocyte subsets after destabilization of the medial meniscus in mice.
J Orthop Res;2021Oct; 39 (10) 2270-2280. doi:10.1002/jor.24958
2021		 Abstract PubMed
Yang W, Chiu S, Querrey M, Liu X, Wu Q, Cerier E, Islam MBAR, Schwulst SJ, Budinger GRS, Mohanakumar T, Lecuona E, Bharat A,:
Nonclassical Monocytes Promote Edema in Lung Allografts from Traumatic Brain Injury Donors.
Am J Respir Cell Mol Biol;202103; 64 (3) 391-394. doi:10.1165/rcmb.2020-0137LE
2021		 Abstract PubMed
Zhang J, Wu Q, Johnson CB, Pham G, Kinder JM, Olsson A, Slaughter A, May M, Weinhaus B, D'Alessandro A, Engel JD, Jiang JX, Kofron JM, Huang LF, Prasath VBS, Way SS, Salomonis N, Grimes HL, Lucas D,:
In situ mapping identifies distinct vascular niches for myelopoiesis.
Nature;202102; 590 (7846) 457-462. doi:10.1038/s41586-021-03201-2
2021		 Abstract PubMed
Keerthivasan S, Şenbabaoğlu Y, Martinez-Martin N, Husain B, Verschueren E, Wong A, Yang YA, Sun Y, Pham V, Hinkle T, Oei Y, Madireddi S, Corpuz R, Tam L, Carlisle S, Roose-Girma M, Modrusan Z, Ye Z, Koerber JT, Turley SJ,:
Homeostatic functions of monocytes and interstitial lung macrophages are regulated via collagen domain-binding receptor LAIR1.
Immunity;20210713; 54 (7) 1511-1526. doi:10.1016/j.immuni.2021.06.012
2021		 Abstract PubMed
Das A, Wang X, Kang J, Coulter A, Shetty AC, Bachu M, Brooks SR, Dell'Orso S, Foster BL, Fan X, Ozato K, Somerman MJ, Thumbigere-Math V,:
Monocyte Subsets With High Osteoclastogenic Potential and Their Epigenetic Regulation Orchestrated by IRF8.
J Bone Miner Res;202101; 36 (1) 199-214. doi:10.1002/jbmr.4165
2021		 Abstract PubMed
Ferrao Blanco MN, Bastiaansen Jenniskens YM, Kops N, Chavli A, Narcisi R, Botter SM, Leenen PJM, van Osch GJVM, Fahy N,:
Intra-articular injection of triamcinolone acetonide sustains macrophage levels and aggravates osteophytosis during degenerative joint disease in mice.
Br J Pharmacol;2021Dec14. doi:10.1111/bph.15780
2021		 Abstract PubMed
Gonzalez-Cotto M, Guo L, Karwan M, Sen SK, Barb J, Collado CJ, Elloumi F, Palmieri EM, Boelte K, Kolodgie FD, Finn AV, Biesecker LG, McVicar DW,:
TREML4 Promotes Inflammatory Programs in Human and Murine Macrophages and Alters Atherosclerosis Lesion Composition in the Apolipoprotein E Deficient Mouse.
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2020		 Abstract PubMed
Sun D, Zhang M, Sun P, Liu G, Strickland AB, Chen Y, Fu Y, Yosri M, Shi M:
VCAM1/VLA4 interaction mediates Ly6Clow monocyte recruitment to the brain in a TNFR signaling dependent manner during fungal infection.
PLoS Pathog. 2020 Feb 26;16(2):e1008361. doi: 10.1371/journal.ppat.1008361.
2020		 Abstract PubMed
Yu YA, Malakhau Y, Yu CA, Phelan SJ, Cumming RI, Kan MJ, Mao L, Rajagopal S, Piantadosi CA, Gunn MD:
Nonclassical Monocytes Sense Hypoxia, Regulate Pulmonary Vascular Remodeling, and Promote Pulmonary Hypertension.
J Immunol. 2020 Mar 15;204(6):1474-1485. doi: 10.4049/jimmunol.1900239. Epub 2020
2020		 Abstract PubMed
Giladi A, Wagner LK, Li H, Dörr D, Medaglia C, Paul F, Shemer A, Jung S, Yona S, Mack M, Leutz A, Amit I, Mildner A,:
Cxcl10+ monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation.
Nat Immunol;202005; 21 (5) 525-534. doi:10.1038/s41590-020-0661-1
2020		 Abstract PubMed
Marcovecchio PM, Zhu YP, Hanna RN, Dinh HQ, Tacke R, Wu R, McArdle S, Reynolds S, Araujo DJ, Ley K, Hedrick CC,:
Frontline Science: Kindlin-3 is essential for patrolling and phagocytosis functions of nonclassical monocytes during metastatic cancer surveillance.
J Leukoc Biol;202006; 107 (6) 883-892. doi:10.1002/JLB.4HI0420-098R
2020		 Abstract PubMed
Meghraoui-Kheddar A, Barthelemy S, Boissonnas A, Combadière C,:
Revising CX3CR1 Expression on Murine Classical and Non-classical Monocytes.
Front Immunol;2020; 11 1117. doi:10.3389/fimmu.2020.01117
2020		 Abstract PubMed
Gupta RM, Lee-Kim VS, Libby P:
The March of Monocytes in Atherosclerosis: One Cell at a Time.
Circ Res . 2020 May 8;126(10):1324-1326. doi: 10.1161/CIRCRESAHA.120.316981.
2020		 Abstract PubMed
Roberts ME, Barvalia M, Silva JA, Cederberg RA, Chu W, Wong A, Tai D, Chen S, Matos I, Priatel J, Cullis PR, Harder K:
Deep Phenotyping by Mass Cytometry and Single-Cell RNA-Sequencing Reveals LYN-Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan.
Circ Res. 2020 Mar 10. doi: 10.1161/CIRCRESAHA.119.315708.
2020		 Abstract PubMed
Kimball AS, Obi AT, Luke CE, Dowling AR, Cai Q, Adili R, Jankowski H, Schaller M, Holinstadt M, Jaffer FA, Kunkel SL, Gallagher KA, Henke PK:
Ly6CLo Monocyte/Macrophages are Essential for Thrombus Resolution in a Murine Model of Venous Thrombosis.
Thromb Haemost. 2020 Feb;120(2):289-299. doi: 10.1055/s-0039-3400959. Epub 2019
2020		 Abstract PubMed
Fukushima K, Satoh T, Sugihara F, Sato Y, Okamoto T, Mitsui Y, Yoshio S, Li S, Nojima S, Motooka D, Nakamura S, Kida H, Standley DM, Morii E, Kanto T, Yanagita M, Matsuura Y, Nagasawa T, Kumanogoh A, Akira S:
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2020		 Abstract PubMed
Alkhani A, Levy CS, Tsui M, Rosenberg KA, Polovina K, Mattis AN, Mack M, Van Dyken S, Wang BM, Maher JJ, Nijagal A,:
Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.
Sci Rep;20200428; 10 (1) 7165. doi:10.1038/s41598-020-64158-2
2020		 Abstract PubMed
Turner-Stokes T, Garcia Diaz A, Pinheiro D, Prendecki M, McAdoo SP, Roufosse C, Cook HT, Pusey CD, Woollard KJ,:
Live Imaging of Monocyte Subsets in Immune Complex-Mediated Glomerulonephritis Reveals Distinct Phenotypes and Effector Functions.
J Am Soc Nephrol;202011; 31 (11) 2523-2542. doi:10.1681/ASN.2019121326
2020		 Abstract PubMed
Schuett J, Kreutz J, Grote K, Vlacil AK, Schuett H, Oberoi R, Schmid A, Witten A, Stoll M, Schieffer B, Ruhle F:
Suppressor of Cytokine Signaling 1 is Involved in Gene Regulation Which Controls the Survival of Ly6Clow Monocytes in Mice.
Cell Physiol Biochem. 2019;52(2):336-353. doi: 10.33594/000000024. Epub 2019 Feb
2019		 Abstract PubMed
Sippel TR, Radtke S, Olsen TM, Kiem HP, Rongvaux A:
Human hematopoietic stem cell maintenance and myeloid cell development in next-generation humanized mouse models.
Blood Adv. 2019 Feb 12;3(3):268-274. doi: 10.1182/bloodadvances.2018023887.
2019		 Abstract PubMed
Schyns J, Bai Q, Ruscitti C, Radermecker C, De Schepper S, Chakarov S, Farnir F, Pirottin D, Ginhoux F, Boeckxstaens G, Bureau F, Marichal T:
Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung.
Nat Commun. 2019 Sep 3;10(1):3964. doi: 10.1038/s41467-019-11843-0.
2019		 Abstract PubMed
Schneider CA, Figueroa Velez DX, Azevedo R, Hoover EM, Tran CJ, Lo C, Vadpey O, Gandhi SP, Lodoen MB:
Imaging the dynamic recruitment of monocytes to the blood-brain barrier and specific brain regions during Toxoplasma gondii infection.
Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24796-24807. doi:
2019		 Abstract PubMed
Hou X, Chen G, Bracamonte-Baran W, Choi HS, Diny NL, Sung J, Hughes D, Won T, Wood MK, Talor MV, Hackam DJ, Klingel K, Davogustto G, Taegtmeyer H, Coppens I, Barin JG, Cihakova D:
The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis.
Cell Rep. 2019 Jul 2;28(1):172-189.e7. doi: 10.1016/j.celrep.2019.06.007.
2019		 Abstract PubMed
Bianchini M, Duchene J, Santovito D, Schloss MJ, Evrard M, Winkels H, Aslani M, Mohanta SK, Horckmans M, Blanchet X, Lacy M, von Hundelshausen P, Atzler D, Habenicht A, Gerdes N, Pelisek J, Ng LG, Steffens S, Weber C, Megens RTA:
PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function.
Sci Immunol. 2019 Jun 21;4(36). pii: 4/36/eaar3054. doi:
2019		 Abstract PubMed
Russo MV, Latour LL, McGavern DB:
Distinct myeloid cell subsets promote meningeal remodeling and vascular repair after mild traumatic brain injury.
Nat Immunol. 2018 May;19(5):442-452. doi: 10.1038/s41590-018-0086-2. Epub 2018
2018		 Abstract PubMed
Isobe M, Izawa K, Sugiuchi M, Sakanishi T, Kaitani A, Takamori A, Maehara A, Matsukawa T, Takahashi M, Yamanishi Y, Oki T, Uchida S, Uchida K, Ando T, Maeda K, Nakano N, Yagita H, Takai T, Ogawa H, Okumura K, Kitamura T, Kitaura J:
The CD300e molecule in mice is an immune-activating receptor.
J. Biol. Chem.; 2018 Mar 09; 293(10) 3793-3805. doi:10.1074/jbc.RA117.000696
2018		 Abstract PubMed
Niewold P, Cohen A, van Vreden C, Getts DR, Grau GE, King NJC:
Experimental severe malaria is resolved by targeting newly-identified monocyte subsets using immune-modifying particles combined with artesunate.
Commun Biol. 2018 Dec 13;1:227. doi: 10.1038/s42003-018-0216-2. eCollection 2018.
2018		 Abstract PubMed
Lin Q, Ohtsuji M, Amano H, Tsurui H, Tada N, Sato R, Fukuyama H, Nishimura H, Verbeek JS, Hirose S:
FcgammaRIIb on B Cells and Myeloid Cells Modulates B Cell Activation and Autoantibody Responses via Different but Synergistic Pathways in Lupus-Prone Yaa Mice.
J Immunol. 2018 Dec 1;201(11):3199-3210. doi: 10.4049/jimmunol.1701487. Epub 2018
2018		 Abstract PubMed
Tuohy JL, Fogle JE, Meichner K, Borst LB, Petty CS, Griffith EH, Osborne JA, Lascelles BDX:
Assessment of a novel nanoparticle hyperthermia therapy in a murine model of osteosarcoma.
Vet Surg. 2018 Nov;47(8):1021-1030. doi: 10.1111/vsu.12959. Epub 2018 Oct 11.
2018		 Abstract PubMed
Puchner A, Saferding V, Bonelli M, Mikami Y, Hofmann M, Brunner JS, Caldera M, Goncalves-Alves E, Binder NB, Fischer A, Simader E, Steiner CW, Leiss H, Hayer S, Niederreiter B, Karonitsch T, Koenders MI, Podesser BK, O'Shea JJ, Menche J, Smolen JS, Redlic:
Non-classical monocytes as mediators of tissue destruction in arthritis.
Ann Rheum Dis. 2018 Oct;77(10):1490-1497. doi: 10.1136/annrheumdis-2018-213250.
2018		 Abstract PubMed
Trompette A, Gollwitzer ES, Pattaroni C, Lopez-Mejia IC, Riva E, Pernot J, Ubags N, Fajas L, Nicod LP, Marsland BJ:
Dietary Fiber Confers Protection against Flu by Shaping Ly6c- Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism.
Immunity. 2018 May 15;48(5):992-1005.e8. doi: 10.1016/j.immuni.2018.04.022.
2018		 Abstract PubMed
Westhorpe CLV, Norman MU, Hall P, Snelgrove SL, Finsterbusch M, Li A, Lo C, Tan ZH, Li S, Nilsson SK, Kitching AR, Hickey MJ:
Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes.
Nat Commun; 2018 02 21; 9(1) 747. doi:10.1038/s41467-018-03181-4
2018		 Abstract PubMed
Barbet G, Sander LE, Geswell M, Leonardi I, Cerutti A, Iliev I, Blander JM:
Sensing Microbial Viability through Bacterial RNA Augments T Follicular Helper Cell and Antibody Responses.
Immunity; 2018 Mar 20; 48(3) 584-598. doi:10.1016/j.immuni.2018.02.015
2018		 Abstract PubMed
Getzin T, Krishnasamy K, Gamrekelashvili J, Kapanadze T, Limbourg A, Häger C, Napp LC, Bauersachs J, Haller H, Limbourg FP:
The chemokine receptor CX3CR1 coordinates monocyte recruitment and endothelial regeneration after arterial injury.
EMBO Mol Med; 2018 Feb; 10(2) 151-159. doi:10.15252/emmm.201707502
2018		 Abstract PubMed
Fernández-Caballero T, Álvarez B, Revilla C, Zaldívar-López S, Alonso F, Garrido JJ, Ezquerra Á, Domínguez J:
Phenotypic and functional characterization of porcine bone marrow monocyte subsets.
Dev. Comp. Immunol.; 2018 Apr; 8195-104. doi:10.1016/j.dci.2017.11.012
2018		 Abstract PubMed
Belgiovine C, Bello E, Liguori M, Craparotta I, Mannarino L, Paracchini L, Beltrame L, Marchini S, Galmarini CM, Mantovani A, Frapolli R, Allavena P, D Incalci M:
Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models.
Br. J. Cancer; 2017 Aug 22; 117(5) 628-638. doi:10.1038/bjc.2017.205
2017		 Abstract PubMed
Yáñez A, Coetzee SG, Olsson A, Muench DE, Berman BP, Hazelett DJ, Salomonis N, Grimes HL, Goodridge HS:
Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes.
Immunity; 2017 11 21; 47(5) 890-902. doi:10.1016/j.immuni.2017.10.021
2017		 Abstract PubMed
Pomeroy B, Sipka A, Hussen J, Eger M, Schukken Y, Schuberth HJ:
Counts of bovine monocyte subsets prior to calving are predictive for postpartum occurrence of mastitis and metritis.
Vet. Res.; 2017 02 21; 48(1) 13. doi:10.1186/s13567-017-0415-8
2017		 Abstract PubMed
Grandoni F, Elnaggar MM, Abdellrazeq GS, Signorelli F, Fry LM, Marchitelli C, Hulubei V, Khaliel SA, Torky HA, Davis WC:
Characterization of leukocyte subsets in buffalo (Bubalus bubalis) with cross-reactive monoclonal antibodies specific for bovine MHC class I and class II molecules and leukocyte differentiation molecules.
Dev. Comp. Immunol.; 2017 09; 74101-109. doi:10.1016/j.dci.2017.04.013
2017		 Abstract PubMed
Wolf Y, Shemer A, Polonsky M, Gross M, Mildner A, Yona S, David E, Kim KW, Goldmann T, Amit I, Heikenwalder M, Nedospasov S, Prinz M, Friedman N, Jung S:
Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation.
J. Exp. Med.; 2017 Apr 03; 214(4) 905-917. doi:10.1084/jem.20160499
2017		 Abstract PubMed
Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D:
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.
J. Clin. Invest.; 2017 Aug 01; 127(8) 3039-3051. doi:10.1172/JCI93182
2017		 Abstract PubMed
Mildner A, Schönheit J, Giladi A, David E, Lara-Astiaso D, Lorenzo-Vivas E, Paul F, Chappell-Maor L, Priller J, Leutz A, Amit I, Jung S:
Genomic Characterization of Murine Monocytes Reveals C/EBPbeta Transcription Factor Dependence of Ly6C- Cells.
Immunity; 2017 05 16; 46(5) 849-862. doi:10.1016/j.immuni.2017.04.018
2017		 Abstract PubMed
Marcovecchio PM, Thomas GD, Mikulski Z, Ehinger E, Mueller KAL, Blatchley A, Wu R, Miller YI, Nguyen AT, Taylor AM, McNamara CA, Ley K, Hedrick CC:
Scavenger Receptor CD36 Directs Nonclassical Monocyte Patrolling Along the Endothelium During Early Atherogenesis.
Arterioscler. Thromb. Vasc. Biol.; 2017 Nov; 37(11) 2043-2052. doi:10.1161/ATVBAHA.117.309123
2017		 Abstract PubMed
Makinde HM, Cuda CM, Just TB, Perlman HR, Schwulst SJ:
Nonclassical Monocytes Mediate Secondary Injury, Neurocognitive Outcome, and Neutrophil Infiltration after Traumatic Brain Injury.
J. Immunol.; 2017 11 15; 199(10) 3583-3591. doi:10.4049/jimmunol.1700896
2017		 Abstract PubMed
Lessard AJ, LeBel M, Egarnes B, Préfontaine P, Thériault P, Droit A, Brunet A, Rivest S, Gosselin J:
Triggering of NOD2 Receptor Converts Inflammatory Ly6Chigh into Ly6Clow Monocytes with Patrolling Properties.
Cell Rep; 2017 Aug 22; 20(8) 1830-1843. doi:10.1016/j.celrep.2017.08.009
2017		 Abstract PubMed
Priller J, Böttcher C:
Patrolling monocytes sense peripheral infection and induce cytokine-mediated neuronal dysfunction.
Nat. Med.; 2017 Jun 06; 23(6) 659-661. doi:10.1038/nm.4349
2017		 Abstract PubMed
Zheng Z, Chiu S, Akbarpour M, Sun H, Reyfman PA, Anekalla KR, Abdala-Valencia H, Edgren D, Li W, Kreisel D, Korobova FV, Fernandez R, McQuattie-Pimentel A, Zhang ZJ, Perlman H, Misharin AV, Scott Budinger GR, Bharat A:
Donor pulmonary intravascular nonclassical monocytes recruit recipient neutrophils and mediate primary lung allograft dysfunction.
Sci Transl Med; 2017 Jun 14; 9(394). doi:10.1126/scitranslmed.aal4508
2017		 Abstract PubMed
Rahman K, Vengrenyuk Y, Ramsey SA, Vila NR, Girgis NM, Liu J, Gusarova V, Gromada J, Weinstock A, Moore KJ, Loke P, Fisher EA:
Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression.
J. Clin. Invest.; 2017 Aug 01; 127(8) 2904-2915. doi:10.1172/JCI75005
2017		 Abstract PubMed
Quintar A, McArdle S, Wolf D, Marki A, Ehinger E, Vassallo M, Miller J, Mikulski Z, Ley K, Buscher K:
Endothelial Protective Monocyte Patrolling in Large Arteries Intensified by Western Diet and Atherosclerosis.
Circ. Res.; 2017 May 26; 120(11) 1789-1799. doi:10.1161/CIRCRESAHA.117.310739
2017		 Abstract PubMed
Zakharenko AM, Engin AB, Chernyshev VV, Chaika VV, Ugay SM, Rezaee R, Karimi G, Drozd VA, Nikitina AV, Solomennik SF, Kudryavkina OR, Xin L, Wenpeng Y, Tzatzarakis M, Tsatsakis AM, Golokhvast KS:
Basophil mediated pro-allergic inflammation in vehicle-emitted particles exposure.
Environ. Res.; 2017 Jan; 152308-314. doi:10.1016/j.envres.2016.10.031
2017		 Abstract PubMed
Sher A, Tosh K, Jankovic D:
Innate recognition of Toxoplasma gondii in humans involves a mechanism distinct from that utilized by rodents.
Cell. Mol. Immunol.; 2017 Jan; 14(1) 36-42. doi:10.1038/cmi.2016.12
2017		 Abstract PubMed
Quintar A, McArdle S, Wolf D, Marki A, Ehinger E, Vassallo M, Miller J, Mikulski Z, Ley K, Buscher K:
Endothelial Protective Monocyte Patrolling in Large Arteries Intensified by Western Diet and Atherosclerosis.
Circ. Res.; 2017 May 26; 120(11) 1789-1799. doi:10.1161/CIRCRESAHA.117.310739
2017		 Abstract PubMed
Hamon P, Loyher PL, Baudesson de Chanville C, Licata F, Combadière C, Boissonnas A:
CX3CR1-dependent endothelial margination modulates Ly6Chigh monocyte systemic deployment upon inflammation in mice.
Blood; 2017 03 09; 129(10) 1296-1307. doi:10.1182/blood-2016-08-732164
2017		 Abstract PubMed
Gasco S, Zaragoza P, García-Redondo A, Calvo AC, Osta R:
Inflammatory and non-inflammatory monocytes as novel prognostic biomarkers of survival in SOD1G93A mouse model of Amyotrophic Lateral Sclerosis.
PLoS ONE; 2017; 12(9) 0184626. doi:10.1371/journal.pone.0184626
2017		 Abstract PubMed
Gundra UM, Girgis NM, Gonzalez MA, San Tang M, Van Der Zande HJP, Lin JD, Ouimet M, Ma LJ, Poles J, Vozhilla N, Fisher EA, Moore KJ, Loke P:
Vitamin A mediates conversion of monocyte-derived macrophages into tissue-resident macrophages during alternative activation.
Nat. Immunol.; 2017 06; 18(6) 642-653. doi:10.1038/ni.3734
2017		 Abstract PubMed
Mowat AM, Bain CC:
Alternative monocytes settle in for the long term.
Nat. Immunol.; 2017 05 18; 18(6) 599-600. doi:10.1038/ni.3749
2017		 Abstract PubMed
Béliard S, Le Goff W, Saint-Charles F, Poupel L, Deswaerte V, Bouchareychas L, Huby T, Lesnik P:
Modulation of Gr1low monocyte subset impacts insulin sensitivity and weight gain upon high-fat diet in female mice.
Int J Obes(Lond); 2017 Dec; 41(12) 1805-1814. doi:10.1038/ijo.2017.179
2017		 Abstract PubMed
Tamura A, Hirai H, Yokota A, Kamio N, Sato A, Shoji T, Kashiwagi T, Torikoshi Y, Miura Y, Tenen DG, Maekawa T:
C/EBPbeta is required for survival of Ly6C- monocytes.
Blood; 2017 10 19; 130(16) 1809-1818. doi:10.1182/blood-2017-03-772962
2017		 Abstract PubMed
Satoh T, Nakagawa K, Sugihara F, Kuwahara R, Ashihara M, Yamane F, Minowa Y, Fukushima K, Ebina I, Yoshioka Y, Kumanogoh A, Akira S:
Identification of an atypical monocyte and committed progenitor involved in fibrosis.
Nature; 2017 01 05; 541(7635) 96-101. doi:10.1038/nature20611
2017		 Abstract PubMed
Imhof BA, Jemelin S, Emre Y:
Toll-like receptors elicit different recruitment kinetics of monocytes and neutrophils in mouse acute inflammation.
Eur. J. Immunol.; 2017 06; 47(6) 1002-1008. doi:10.1002/eji.201746983
2017		 Abstract PubMed
Béliard S, Le Goff W, Saint-Charles F, Poupel L, Deswaerte V, Bouchareychas L, Huby T, Lesnik P:
Modulation of Gr1low monocyte subset impacts insulin sensitivity and weight gain upon high-fat diet in female mice.
Int J Obes(Lond); 2017 Dec; 41(12) 1805-1814. doi:10.1038/ijo.2017.179
2017		 Abstract PubMed
Olingy CE, San Emeterio CL, Ogle ME, Krieger JR, Bruce AC, Pfau DD, Jordan BT, Peirce SM, Botchwey EA:
Non-classical monocytes are biased progenitors of wound healing macrophages during soft tissue injury.
Sci Rep; 2017 03 27; 7(1) 447. doi:10.1038/s41598-017-00477-1
2017		 Abstract PubMed
Garré JM, Silva HM, Lafaille JJ, Yang G:
CX3CR1+ monocytes modulate learning and learning-dependent dendritic spine remodeling via TNF-alpha.
Nat. Med.; 2017 Jun; 23(6) 714-722. doi:10.1038/nm.4340
2017		 Abstract PubMed
Elderman M, van Beek A, Brandsma E, de Haan B, Savelkoul H, de Vos P, Faas M:
Sex impacts Th1 cells, Tregs, and DCs in both intestinal and systemic immunity in a mouse strain and location-dependent manner.
Biol Sex Differ; 2016; 721. doi:10.1186/s13293-016-0075-9
2016		 Abstract PubMed
Briseño CG, Haldar M, Kretzer NM, Wu X, Theisen DJ, Kc W, Durai V, Grajales-Reyes GE, Iwata A, Bagadia P, Murphy TL, Murphy KM:
Distinct Transcriptional Programs Control Cross-Priming in Classical and Monocyte-Derived Dendritic Cells.
Cell Rep; 2016 06 14; 15(11) 2462-74. doi:10.1016/j.celrep.2016.05.025
2016		 Abstract PubMed
Briseño CG, Haldar M, Kretzer NM, Wu X, Theisen DJ, Kc W, Durai V, Grajales-Reyes GE, Iwata A, Bagadia P, Murphy TL, Murphy KM:
Distinct Transcriptional Programs Control Cross-Priming in Classical and Monocyte-Derived Dendritic Cells.
Cell Rep; 2016 06 14; 15(11) 2462-74. doi:10.1016/j.celrep.2016.05.025
2016		 Abstract PubMed
Saito Y, Ellegast JM, Rafiei A, Song Y, Kull D, Heikenwalder M, Rongvaux A, Halene S, Flavell RA, Manz MG:
Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice.
Blood; 2016 10 06; 128(14) 1829-1833. doi:10.1182/blood-2015-10-676452
2016		 Abstract PubMed
Lund H, Boysen P, Åkesson CP, Lewandowska-Sabat AM, Storset AK:
Transient Migration of Large Numbers of CD14(++) CD16(+) Monocytes to the Draining Lymph Node after Onset of Inflammation.
Front Immunol; 2016; 7322. doi:10.3389/fimmu.2016.00322
2016		 Abstract PubMed
Hussen J, Koy M, Petzl W, Schuberth HJ:
Neutrophil degranulation differentially modulates phenotype and function of bovine monocyte subsets.
Innate Immun; 2016 Feb; 22(2) 124-37. doi:10.1177/1753425915620911
2016		 Abstract PubMed
Elnaggar MM, Abdellrazeq GS, Mack V, Fry LM, Davis WC, Park KT:
Characterization and use of new monoclonal antibodies to CD11c, CD14, and CD163 to analyze the phenotypic complexity of ruminant monocyte subsets.
Vet. Immunol. Immunopathol.; 2016 Oct 01; 17857-63. doi:10.1016/j.vetimm.2016.06.010
2016		 Abstract PubMed
Skuljec J, Cabanski M, Surdziel E, Lachmann N, Brennig S, Pul R, Jirmo AC, Habener A, Visic J, Dalüge K, Hennig C, Moritz T, Happle C, Hansen G:
Monocyte/macrophage lineage commitment and distribution are affected by the lack of regulatory T cells in scurfy mice.
Eur. J. Immunol.; 2016 07; 46(7) 1656-68. doi:10.1002/eji.201546200
2016		 Abstract PubMed
Jackson WD, Weinrich TW, Woollard KJ:
Very-low and low-density lipoproteins induce neutral lipid accumulation and impair migration in monocyte subsets.
Sci Rep; 2016 Jan 29; 620038. doi:10.1038/srep20038
2016		 Abstract PubMed
Kocher T, Asslaber D, Zaborsky N, Flenady S, Denk U, Reinthaler P, Ablinger M, Geisberger R, Bauer JW, Seiffert M, Hartmann TN, Greil R, Egle A, Piñón Hofbauer J:
CD4+ T cells, but not non-classical monocytes, are dispensable for the development of chronic lymphocytic leukemia in the TCL1-tg murine model.
Leukemia; 2016 06; 30(6) 1409-13. doi:10.1038/leu.2015.307
2016		 Abstract PubMed
Scott CL, Zheng F, De Baetselier P, Martens L, Saeys Y, De Prijck S, Lippens S, Abels C, Schoonooghe S, Raes G, Devoogdt N, Lambrecht BN, Beschin A, Guilliams M:
Bone marrow-derived monocytes give rise to self-renewing and fully differentiated Kupffer cells.
Nat Commun; 2016 Jan 27; 710321. doi:10.1038/ncomms10321
2016		 Abstract PubMed
Stifter SA, Bhattacharyya N, Pillay R, Flórido M, Triccas JA, Britton WJ, Feng CG:
Functional Interplay between Type I and II Interferons Is Essential to Limit Influenza A Virus-Induced Tissue Inflammation.
PLoS Pathog.; 2016 Jan; 12(1) 1005378. doi:10.1371/journal.ppat.1005378
2016		 Abstract PubMed
Thomas GD, Hanna RN, Vasudevan NT, Hamers AA, Romanoski CE, McArdle S, Ross KD, Blatchley A, Yoakum D, Hamilton BA, Mikulski Z, Jain MK, Glass CK, Hedrick CC:
Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function.
Immunity; 2016 11 15; 45(5) 975-987. doi:10.1016/j.immuni.2016.10.011
2016		 Abstract PubMed
Sivakumaran S, Henderson S, Ward S, Sousa PS, Manzo T, Zhang L, Conlan T, Means TK, D Aveni M, Hermine O, Rubio MT, Chakraverty R, Bennett CL:
Depletion of CD11c+ cells in the CD11c.DTR model drives expansion of unique CD64+ Ly6C+ monocytes that are poised to release TNF-alpha.
Eur. J. Immunol.; 2016 Jan; 46(1) 192-203. doi:10.1002/eji.201545789
2016		 Abstract PubMed
Kameda Y, Hanayama M, Kishimoto A, Kume M, Yamamoto K, Matsumoto N:
Dendritic cell inhibitory receptor 4 (DCIR4) is preferentially expressed on inflammatory and patrolling monocytes.
Biochem. Biophys. Res. Commun.; 2016 11 11; 480(2) 215-221. doi:10.1016/j.bbrc.2016.10.030
2016		 Abstract PubMed
Finsterbusch M, Hall P, Li A, Devi S, Westhorpe CL, Kitching AR, Hickey MJ:
Patrolling monocytes promote intravascular neutrophil activation and glomerular injury in the acutely inflamed glomerulus.
Proc. Natl. Acad. Sci. U.S.A.; 2016 08 30; 113(35) 5172-81. doi:10.1073/pnas.1606253113
2016		 Abstract PubMed
Mildner A, Marinkovic G, Jung S:
Murine Monocytes: Origins, Subsets, Fates, and Functions.
Microbiol Spectr; 2016 10; 4(5). doi:10.1128/microbiolspec.MCHD-0033-2016
2016		 Abstract PubMed
Brunet A, LeBel M, Egarnes B, Paquet-Bouchard C, Lessard AJ, Brown JP, Gosselin J:
NR4A1-dependent Ly6Clow monocytes contribute to reducing joint inflammation in arthritic mice through Treg cells.
Eur. J. Immunol.; 2016 12; 46(12) 2789-2800. doi:10.1002/eji.201646406
2016		 Abstract PubMed
Imhof BA, Jemelin S, Ballet R, Vesin C, Schapira M, Karaca M, Emre Y:
CCN1/CYR61-mediated meticulous patrolling by Ly6Clow monocytes fuels vascular inflammation.
Proc. Natl. Acad. Sci. U.S.A.; 2016 08 16; 113(33) 4847-56. doi:10.1073/pnas.1607710113
2016		 Abstract PubMed
Chong SZ, Evrard M, Devi S, Chen J, Lim JY, See P, Zhang Y, Adrover JM, Lee B, Tan L, Li JL, Liong KH, Phua C, Balachander A, Boey A, Liebl D, Tan SM, Chan JK, Balabanian K, Harris JE, Bianchini M, Weber C, Duchene J, Lum J, Poidinger M, Chen Q, Rénia L, :
CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses.
J. Exp. Med.; 2016 Oct 17; 213(11) 2293-2314
2016		 Abstract PubMed
Herbin O, Regelmann AG, Ramkhelawon B, Weinstein EG, Moore KJ, Alexandropoulos K:
Monocyte Adhesion and Plaque Recruitment During Atherosclerosis Development Is Regulated by the Adapter Protein Chat-H/SHEP1.
Arterioscler. Thromb. Vasc. Biol.; 2016 Sep; 36(9) 1791-801. doi:10.1161/ATVBAHA.116.308014
2016		 Abstract PubMed
Gamrekelashvili J, Giagnorio R, Jussofie J, Soehnlein O, Duchene J, Briseño CG, Ramasamy SK, Krishnasamy K, Limbourg A, Kapanadze T, Ishifune C, Hinkel R, Radtke F, Strobl LJ, Zimber-Strobl U, Napp LC, Bauersachs J, Haller H, Yasutomo K, Kupatt C, Murphy :
Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.
Nat Commun; 2016 Aug 31; 712597. doi:10.1038/ncomms12597
2016		 Abstract PubMed
Cassetta L, Pollard JW:
Cancer immunosurveillance: role of patrolling monocytes.
Cell Res.; 2016 Jan; 26(1) 3-4. doi:10.1038/cr.2015.144
2016		 Abstract PubMed
Deloizy C, Bouguyon E, Fossum E, Sebo P, Osicka R, Bole A, Pierres M, Biacchesi S, Dalod M, Bogen B, Bertho N, Schwartz-Cornil I:
Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1.
Dev. Comp. Immunol.; 2016 12; 6531-40. doi:10.1016/j.dci.2016.06.015
2016		 Abstract PubMed
Hanna BS, McClanahan F, Yazdanparast H, Zaborsky N, Kalter V, Rößner PM, Benner A, Dürr C, Egle A, Gribben JG, Lichter P, Seiffert M:
Depletion of CLL-associated patrolling monocytes and macrophages controls disease development and repairs immune dysfunction in vivo.
Leukemia; 2016 Mar; 30(3) 570-9. doi:10.1038/leu.2015.305
2016		 Abstract PubMed
Saja MF, Baudino L, Jackson WD, Cook HT, Malik TH, Fossati-Jimack L, Ruseva M, Pickering MC, Woollard KJ, Botto M:
Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1(low) Monocytes.
Cell Rep; 2015 Sep 22; 12(11) 1802-15. doi:10.1016/j.celrep.2015.08.020
2015		 Abstract PubMed
Rodero MP, Poupel L, Loyher PL, Hamon P, Licata F, Pessel C, Hume DA, Combadière C, Boissonnas A:
Immune surveillance of the lung by migrating tissue monocytes.
Elife; 2015 Jul 13; 407847. doi:10.7554/eLife.07847
2015		 Abstract PubMed
Biburger M, Trenkwald I, Nimmerjahn F:
Three blocks are not enough--Blocking of the murine IgG receptor FcgammaRIV is crucial for proper characterization of cells by FACS analysis.
Eur. J. Immunol.; 2015 Sep; 45(9) 2694-7. doi:10.1002/eji.201545463
2015		 Abstract PubMed
Morias Y, Abels C, Laoui D, Van Overmeire E, Guilliams M, Schouppe E, Tacke F, deVries CJ, De Baetselier P, Beschin A:
Ly6C- Monocytes Regulate Parasite-Induced Liver Inflammation by Inducing the Differentiation of Pathogenic Ly6C+ Monocytes into Macrophages.
PLoS Pathog.; 2015 May; 11(5) 1004873. doi:10.1371/journal.ppat.1004873
2015		 Abstract PubMed
Mellak S, Ait-Oufella H, Esposito B, Loyer X, Poirier M, Tedder TF, Tedgui A, Mallat Z, Potteaux S:
Angiotensin II mobilizes spleen monocytes to promote the development of abdominal aortic aneurysm in Apoe-/- mice.
Arterioscler. Thromb. Vasc. Biol.; 2015 Feb; 35(2) 378-88. doi:10.1161/ATVBAHA.114.304389
2015		 Abstract PubMed
Varol C, Mildner A, Jung S:
Macrophages: development and tissue specialization.
Annu. Rev. Immunol.; 2015; 33643-75. doi:10.1146/annurev-immunol-032414-112220
2015		 Abstract PubMed
Tipton TR, Mockridge CI, French RR, Tutt AL, Cragg MS, Beers SA:
Anti-mouse FcgammaRIV antibody 9E9 also blocks FcgammaRIII in vivo.
Blood; 2015 Dec 10; 126(24) 2643-5. doi:10.1182/blood-2015-09-671339
2015		 Abstract PubMed
Blériot C, Dupuis T, Jouvion G, Eberl G, Disson O, Lecuit M:
Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection.
Immunity; 2015 Jan 20; 42(1) 145-58. doi:10.1016/j.immuni.2014.12.020
2015		 Abstract PubMed
Hanna RN, Cekic C, Sag D, Tacke R, Thomas GD, Nowyhed H, Herrley E, Rasquinha N, McArdle S, Wu R, Peluso E, Metzger D, Ichinose H, Shaked I, Chodaczek G, Biswas SK, Hedrick CC:
Patrolling monocytes control tumor metastasis to the lung.
Science; 2015 Nov 20; 350(6263) 985-90. doi:10.1126/science.aac9407
2015		 Abstract PubMed
Dal-Secco D, Wang J, Zeng Z, Kolaczkowska E, Wong CH, Petri B, Ransohoff RM, Charo IF, Jenne CN, Kubes P:
A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury.
J. Exp. Med.; 2015 Apr 06; 212(4) 447-56. doi:10.1084/jem.20141539
2015		 Abstract PubMed
Düvel A, Maaß J, Heppelmann M, Hussen J, Koy M, Piechotta M, Sandra O, Smith DG, Sheldon IM, Dieuzy-Labaye I, Zieger P, Schuberth HJ:
Peripheral blood leukocytes of cows with subclinical endometritis show an altered cellular composition and gene expression.
Theriogenology; 2014 Apr 15; 81(7) 906-17. doi:10.1016/j.theriogenology.2014.01.007
2014		 Abstract PubMed
Molawi K, Wolf Y, Kandalla PK, Favret J, Hagemeyer N, Frenzel K, Pinto AR, Klapproth K, Henri S, Malissen B, Rodewald HR, Rosenthal NA, Bajenoff M, Prinz M, Jung S, Sieweke MH:
Progressive replacement of embryo-derived cardiac macrophages with age.
J. Exp. Med.; 2014 Oct 20; 211(11) 2151-8. doi:10.1084/jem.20140639
2014		 Abstract PubMed
Ji WJ, Ma YQ, Zhou X, Zhang YD, Lu RY, Sun HY, Guo ZZ, Zhang Z, Li YM, Wei LQ:
Temporal and spatial characterization of mononuclear phagocytes in circulating, lung alveolar and interstitial compartments in a mouse model of bleomycin-induced pulmonary injury.
J. Immunol. Methods; 2014 Jan 31; 403(1-2) 7-16. doi:10.1016/j.jim.2013.11.012
2014		 Abstract PubMed
Ngo LY, Kasahara S, Kumasaka DK, Knoblaugh SE, Jhingran A, Hohl TM:
Inflammatory monocytes mediate early and organ-specific innate defense during systemic candidiasis.
J. Infect. Dis.; 2014 Jan 01; 209(1) 109-19. doi:10.1093/infdis/jit413
2014		 Abstract PubMed
Oberbarnscheidt MH, Zeng Q, Li Q, Dai H, Williams AL, Shlomchik WD, Rothstein DM, Lakkis FG:
Non-self recognition by monocytes initiates allograft rejection.
J. Clin. Invest.; 2014 Aug; 124(8) 3579-89. doi:10.1172/JCI74370
2014		 Abstract PubMed
Sauter KA, Pridans C, Sehgal A, Bain CC, Scott C, Moffat L, Rojo R, Stutchfield BM, Davies CL, Donaldson DS, Renault K, McColl BW, Mowat AM, Serrels A, Frame MC, Mabbott NA, Hume DA:
The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration.
PLoS ONE; 2014; 9(8) 105429. doi:10.1371/journal.pone.0105429
2014		 Abstract PubMed
Hoffmann J, Ospelt M, Troidl C, Voss S, Liebetrau C, Kim WK, Rolf A, Wietelmann A, Braun T, Troidl K, Sadayappan S, Barefield D, Hamm C, Nef H, Möllmann H:
Sham surgery and inter-individual heterogeneity are major determinants of monocyte subset kinetics in a mouse model of myocardial infarction.
PLoS ONE; 2014; 9(6) 98456. doi:10.1371/journal.pone.0098456
2014		 Abstract PubMed
Alexander KA, Flynn R, Lineburg KE, Kuns RD, Teal BE, Olver SD, Lor M, Raffelt NC, Koyama M, Leveque L, Le Texier L, Melino M, Markey KA, Varelias A, Engwerda C, Serody JS, Janela B, Ginhoux F, Clouston AD, Blazar BR, Hill GR, MacDonald KP:
CSF-1-dependant donor-derived macrophages mediate chronic graft-versus-host disease.
J. Clin. Invest.; 2014 Oct; 124(10) 4266-80. doi:10.1172/JCI75935
2014		 Abstract PubMed
Daley-Bauer LP, Roback LJ, Wynn GM, Mocarski ES:
Cytomegalovirus hijacks CX3CR1(hi) patrolling monocytes as immune-privileged vehicles for dissemination in mice.
Cell Host Microbe; 2014 Mar 12; 15(3) 351-62. doi:10.1016/j.chom.2014.02.002
2014		 Abstract PubMed
Getts DR, Terry RL, Getts MT, Deffrasnes C, Müller M, van Vreden C, Ashhurst TM, Chami B, McCarthy D, Wu H, Ma J, Martin A, Shae LD, Witting P, Kansas GS, Kühn J, Hafezi W, Campbell IL, Reilly D, Say J, Brown L, White MY, Cordwell SJ, Chadban SJ, Thorp EB:
Therapeutic inflammatory monocyte modulation using immune-modifying microparticles.
Sci Transl Med; 2014 Jan 15; 6(219) 219. doi:10.1126/scitranslmed.3007563
2014		 Abstract PubMed
Misharin AV, Cuda CM, Saber R, Turner JD, Gierut AK, Haines GK, Berdnikovs S, Filer A, Clark AR, Buckley CD, Mutlu GM, Budinger GR, Perlman H:
Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice.
Cell Rep; 2014 Oct 23; 9(2) 591-604. doi:10.1016/j.celrep.2014.09.032
2014		 Abstract PubMed
Li Y, Chen Q, Zheng D, Yin L, Chionh YH, Wong LH, Tan SQ, Tan TC, Chan JK, Alonso S, Dedon PC, Lim B, Chen J:
Induction of functional human macrophages from bone marrow promonocytes by M-CSF in humanized mice.
J. Immunol.; 2013 Sep 15; 191(6) 3192-9. doi:10.4049/jimmunol.1300742
2013		 Abstract PubMed
Nguyen KD, Fentress SJ, Qiu Y, Yun K, Cox JS, Chawla A:
Circadian gene Bmal1 regulates diurnal oscillations of Ly6C(hi) inflammatory monocytes.
Science; 2013 Sep 27; 341(6153) 1483-8. doi:10.1126/science.1240636
2013		 Abstract PubMed
Kurotaki D, Osato N, Nishiyama A, Yamamoto M, Ban T, Sato H, Nakabayashi J, Umehara M, Miyake N, Matsumoto N, Nakazawa M, Ozato K, Tamura T:
Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation.
Blood; 2013 Mar 07; 121(10) 1839-49. doi:10.1182/blood-2012-06-437863
2013		 Abstract PubMed
Debien E, Mayol K, Biajoux V, Daussy C, De Aguero MG, Taillardet M, Dagany N, Brinza L, Henry T, Dubois B, Kaiserlian D, Marvel J, Balabanian K, Walzer T:
S1PR5 is pivotal for the homeostasis of patrolling monocytes.
Eur. J. Immunol.; 2013 Jun; 43(6) 1667-75. doi:10.1002/eji.201343312
2013		 Abstract PubMed
Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, Johnson TE, Ivanov S, Duan Q, Bala S, Condon T, van Rooijen N, Grainger JR, Belkaid Y, Ma ayan A, Riches DW, Yokoyama WM, Ginhoux F, Henson PM, Randolph GJ:
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes.
Immunity; 2013 Sep 19; 39(3) 599-610. doi:10.1016/j.immuni.2013.08.007
2013		 Abstract PubMed
Michaud JP, Bellavance MA, Préfontaine P, Rivest S:
Real-time in vivo imaging reveals the ability of monocytes to clear vascular amyloid beta.
Cell Rep; 2013 Nov 14; 5(3) 646-53. doi:10.1016/j.celrep.2013.10.010
2013		 Abstract PubMed
Soehnlein O, Drechsler M, Döring Y, Lievens D, Hartwig H, Kemmerich K, Ortega-Gómez A, Mandl M, Vijayan S, Projahn D, Garlichs CD, Koenen RR, Hristov M, Lutgens E, Zernecke A, Weber C:
Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes.
EMBO Mol Med; 2013 Mar; 5(3) 471-81. doi:10.1002/emmm.201201717
2013		 Abstract PubMed
Swirski FK, Nahrendorf M:
Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure.
Science; 2013 Jan 11; 339(6116) 161-6. doi:10.1126/science.1230719
2013		 Abstract PubMed
Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, :
Genomic responses in mouse models poorly mimic human inflammatory diseases.
Proc. Natl. Acad. Sci. U.S.A.; 2013 Feb 26; 110(9) 3507-12. doi:10.1073/pnas.1222878110
2013		 Abstract PubMed
Yona S, Kim KW, Wolf Y, Mildner A, Varol D, Breker M, Strauss-Ayali D, Viukov S, Guilliams M, Misharin A, Hume DA, Perlman H, Malissen B, Zelzer E, Jung S:
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis.
Immunity; 2013 Jan 24; 38(1) 79-91. doi:10.1016/j.immuni.2012.12.001
2013		 Abstract PubMed
Thawer SG, Mawhinney L, Chadwick K, de Chickera SN, Weaver LC, Brown A, Dekaban GA:
Temporal changes in monocyte and macrophage subsets and microglial macrophages following spinal cord injury in the Lys-Egfp-ki mouse model.
J. Neuroimmunol.; 2013 Aug 15; 261(1-2) 7-20. doi:10.1016/j.jneuroim.2013.04.008
2013		 Abstract PubMed
Varga T, Mounier R, Gogolak P, Poliska S, Chazaud B, Nagy L:
Tissue LyC6- macrophages are generated in the absence of circulating LyC6- monocytes and Nur77 in a model of muscle regeneration.
J. Immunol.; 2013 Dec 01; 191(11) 5695-701. doi:10.4049/jimmunol.1301445
2013		 Abstract PubMed
Awojoodu AO, Ogle ME, Sefcik LS, Bowers DT, Martin K, Brayman KL, Lynch KR, Peirce-Cottler SM, Botchwey E:
Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis.
Proc. Natl. Acad. Sci. U.S.A.; 2013 Aug 20; 110(34) 13785-90. doi:10.1073/pnas.1221309110
2013		 Abstract PubMed
Beschin A, De Baetselier P, Van Ginderachter JA:
Contribution of myeloid cell subsets to liver fibrosis in parasite infection.
J. Pathol.; 2013 Jan; 229(2) 186-97. doi:10.1002/path.4112
2013		 Abstract PubMed
Chao LC, Soto E, Hong C, Ito A, Pei L, Chawla A, Conneely OM, Tangirala RK, Evans RM, Tontonoz P:
Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice.
J. Lipid Res.; 2013 Mar; 54(3) 806-15. doi:10.1194/jlr.M034157
2013		 Abstract PubMed
Breslin WL, Strohacker K, Carpenter KC, Haviland DL, McFarlin BK:
Mouse blood monocytes: standardizing their identification and analysis using CD115.
J. Immunol. Methods; 2013 Apr 30; 390(1-2) 1-8. doi:10.1016/j.jim.2011.03.005
2013		 Abstract PubMed
Hettinger J, Richards DM, Hansson J, Barra MM, Joschko AC, Krijgsveld J, Feuerer M:
Origin of monocytes and macrophages in a committed progenitor.
Nat. Immunol.; 2013 Aug; 14(8) 821-30. doi:10.1038/ni.2638
2013		 Abstract PubMed
Carlin LM, Stamatiades EG, Auffray C, Hanna RN, Glover L, Vizcay-Barrena G, Hedrick CC, Cook HT, Diebold S, Geissmann F:
Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal.
Cell; 2013 Apr 11; 153(2) 362-75. doi:10.1016/j.cell.2013.03.010
2013		 Abstract PubMed
Zigmond E, Varol C, Farache J, Elmaliah E, Satpathy AT, Friedlander G, Mack M, Shpigel N, Boneca IG, Murphy KM, Shakhar G, Halpern Z, Jung S:
Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells.
Immunity; 2012 Dec 14; 37(6) 1076-90. doi:10.1016/j.immuni.2012.08.026
2012		 Abstract PubMed
Leuschner F, Rauch PJ, Ueno T, Gorbatov R, Marinelli B, Lee WW, Dutta P, Wei Y, Robbins C, Iwamoto Y, Sena B, Chudnovskiy A, Panizzi P, Keliher E, Higgins JM, Libby P, Moskowitz MA, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M:
Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis.
J. Exp. Med.; 2012 Jan 16; 209(1) 123-37. doi:10.1084/jem.20111009
2012		 Abstract PubMed
Carrer A, Moimas S, Zacchigna S, Pattarini L, Zentilin L, Ruozi G, Mano M, Sinigaglia M, Maione F, Serini G, Giraudo E, Bussolino F, Giacca M:
Neuropilin-1 identifies a subset of bone marrow Gr1- monocytes that can induce tumor vessel normalization and inhibit tumor growth.
Cancer Res.; 2012 Dec 15; 72(24) 6371-81. doi:10.1158/0008-5472.CAN-12-0762
2012		 Abstract PubMed
Lenzo JC, Turner AL, Cook AD, Vlahos R, Anderson GP, Reynolds EC, Hamilton JA:
Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation.
Immunol. Cell Biol.; 2012 Apr; 90(4) 429-40. doi:10.1038/icb.2011.58
2012		 Abstract PubMed
Dhaliwal K, Scholefield E, Ferenbach D, Gibbons M, Duffin R, Dorward DA, Morris AC, Humphries D, MacKinnon A, Wilkinson TS, Wallace WA, van Rooijen N, Mack M, Rossi AG, Davidson DJ, Hirani N, Hughes J, Haslett C, Simpson AJ:
Monocytes control second-phase neutrophil emigration in established lipopolysaccharide-induced murine lung injury.
Am. J. Respir. Crit. Care Med.; 2012 Sep 15; 186(6) 514-24. doi:10.1164/rccm.201112-2132OC
2012		 Abstract PubMed
Strohacker K, Breslin WL, Carpenter KC, McFarlin BK:
Aged mice have increased inflammatory monocyte concentration and altered expression of cell-surface functional receptors.
J. Biosci.; 2012 Mar; 37(1) 55-62
2012		 Abstract PubMed
Strohacker K, Breslin WL, Carpenter KC, McFarlin BK:
Aged mice have increased inflammatory monocyte concentration and altered expression of cell-surface functional receptors.
J. Biosci.; 2012 Mar; 37(1) 55-62
2012		 Abstract PubMed
Huang Y, Yin H, Wang J, Liu Q, Wu C, Chen K:
Aberrant expression of FcgammaRIIIA (CD16) contributes to the development of atherosclerosis.
Gene; 2012 Apr 25; 498(1) 91-5. doi:10.1016/j.gene.2012.02.006
2012		 Abstract PubMed
Meisner JK, Song J, Price RJ:
Arteriolar and venular remodeling are differentially regulated by bone marrow-derived cell-specific CX3CR1 and CCR2 expression.
PLoS ONE; 2012; 7(9) 46312. doi:10.1371/journal.pone.0046312
2012		 Abstract PubMed
Saha P, Geissmann F:
Toward a functional characterization of blood monocytes.
Immunol. Cell Biol.; 2011 Jan; 89(1) 2-4. doi:10.1038/icb.2010.130
2011		 Abstract PubMed
Potteaux S, Gautier EL, Hutchison SB, van Rooijen N, Rader DJ, Thomas MJ, Sorci-Thomas MG, Randolph GJ:
Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/- mice during disease regression.
J. Clin. Invest.; 2011 May; 121(5) 2025-36. doi:10.1172/JCI43802
2011		 Abstract PubMed
Biburger M, Aschermann S, Schwab I, Lux A, Albert H, Danzer H, Woigk M, Dudziak D, Nimmerjahn F:
Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo.
Immunity; 2011 Dec 23; 35(6) 932-44. doi:10.1016/j.immuni.2011.11.009
2011		 Abstract PubMed
O Dea KP, Dokpesi JO, Tatham KC, Wilson MR, Takata M:
Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway.
Am. J. Physiol. Lung Cell Mol. Physiol.; 2011 Nov; 301(5) 812-21. doi:10.1152/ajplung.00092.2011
2011		 Abstract PubMed
Iijima N, Mattei LM, Iwasaki A:
Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue.
Proc. Natl. Acad. Sci. U.S.A.; 2011 Jan 04; 108(1) 284-9. doi:10.1073/pnas.1005201108
2011		 Abstract PubMed
Hanna RN, Carlin LM, Hubbeling HG, Nackiewicz D, Green AM, Punt JA, Geissmann F, Hedrick CC:
The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes.
Nat. Immunol.; 2011 Jul 03; 12(8) 778-85. doi:10.1038/ni.2063
2011		 Abstract PubMed
Santiago-Raber ML, Baudino L, Alvarez M, van Rooijen N, Nimmerjahn F, Izui S:
TLR7/9-mediated monocytosis and maturation of Gr-1(hi) inflammatory monocytes towards Gr-1(lo) resting monocytes implicated in murine lupus.
J. Autoimmun.; 2011 Nov; 37(3) 171-9. doi:10.1016/j.jaut.2011.05.015
2011		 Abstract PubMed
Kim KW, Vallon-Eberhard A, Zigmond E, Farache J, Shezen E, Shakhar G, Ludwig A, Lira SA, Jung S:
In vivo structure/function and expression analysis of the CX3C chemokine fractalkine.
Blood; 2011 Nov 24; 118(22) 156-67. doi:10.1182/blood-2011-04-348946
2011		 Abstract PubMed
Cochain C, Rodero MP, Vilar J, Récalde A, Richart AL, Loinard C, Zouggari Y, Guérin C, Duriez M, Combadière B, Poupel L, Lévy BI, Mallat Z, Combadière C, Silvestre JS:
Regulation of monocyte subset systemic levels by distinct chemokine receptors controls post-ischaemic neovascularization.
Cardiovasc. Res.; 2010 Oct 01; 88(1) 186-95. doi:10.1093/cvr/cvq153
2010		 Abstract PubMed
Drevets DA, Schawang JE, Mandava VK, Dillon MJ, Leenen PJ:
Severe Listeria monocytogenes infection induces development of monocytes with distinct phenotypic and functional features.
J. Immunol.; 2010 Aug 15; 185(4) 2432-41. doi:10.4049/jimmunol.1000486
2010		 Abstract PubMed
MacDonald KP, Palmer JS, Cronau S, Seppanen E, Olver S, Raffelt NC, Kuns R, Pettit AR, Clouston A, Wainwright B, Branstetter D, Smith J, Paxton RJ, Cerretti DP, Bonham L, Hill GR, Hume DA:
An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation.
Blood; 2010 Nov 11; 116(19) 3955-63. doi:10.1182/blood-2010-02-266296
2010		 Abstract PubMed
Saederup N, Cardona AE, Croft K, Mizutani M, Cotleur AC, Tsou CL, Ransohoff RM, Charo IF:
Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice.
PLoS ONE; 2010 Oct 27; 5(10) 13693. doi:10.1371/journal.pone.0013693
2010		 Abstract PubMed
Geissmann F, Gordon S, Hume DA, Mowat AM, Randolph GJ:
Unravelling mononuclear phagocyte heterogeneity.
Nat. Rev. Immunol.; 2010 06; 10(6) 453-60. doi:10.1038/nri2784
2010		 Abstract PubMed
Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K:
Development of monocytes, macrophages, and dendritic cells.
Science; 2010 Feb 05; 327(5966) 656-61. doi:10.1126/science.1178331
2010		 Abstract PubMed
Zhou J, Tang PC, Qin L, Gayed PM, Li W, Skokos EA, Kyriakides TR, Pober JS, Tellides G:
CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses.
J. Exp. Med.; 2010 Aug 30; 207(9) 1951-66. doi:10.1084/jem.20100098
2010		 Abstract PubMed
Nagaoka K, Takahara K, Minamino K, Takeda T, Yoshida Y, Inaba K:
Expression of C-type lectin, SIGNR3, on subsets of dendritic cells, macrophages, and monocytes.
J. Leukoc. Biol.; 2010 Nov; 88(5) 913-24. doi:10.1189/jlb.0510251
2010		 Abstract PubMed
Nahrendorf M, Pittet MJ, Swirski FK:
Monocytes: protagonists of infarct inflammation and repair after myocardial infarction.
Circulation; 2010 Jun 08; 121(22) 2437-45. doi:10.1161/CIRCULATIONAHA.109.916346
2010		 Abstract PubMed
Swirski FK, Wildgruber M, Ueno T, Figueiredo JL, Panizzi P, Iwamoto Y, Zhang E, Stone JR, Rodriguez E, Chen JW, Pittet MJ, Weissleder R, Nahrendorf M:
Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice.
J. Clin. Invest.; 2010 Jul; 120(7) 2627-34. doi:10.1172/JCI42304
2010		 Abstract PubMed
Drevets DA, Dillon MJ, Schawang JE, Stoner JA, Leenen PJ:
IFN-gamma triggers CCR2-independent monocyte entry into the brain during systemic infection by virulent Listeria monocytogenes.
Brain Behav. Immun.; 2010 Aug; 24(6) 919-29. doi:10.1016/j.bbi.2010.02.011
2010		 Abstract PubMed
Swirski FK, Nahrendorf M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ:
Identification of splenic reservoir monocytes and their deployment to inflammatory sites.
Science; 2009 Jul 31; 325(5940) 612-6. doi:10.1126/science.1175202
2009		 Abstract PubMed
Karlmark KR, Weiskirchen R, Zimmermann HW, Gassler N, Ginhoux F, Weber C, Merad M, Luedde T, Trautwein C, Tacke F:
Hepatic recruitment of the inflammatory Gr1+ monocyte subset upon liver injury promotes hepatic fibrosis.
Hepatology; 2009 Jul; 50(1) 261-74. doi:10.1002/hep.22950
2009		 Abstract PubMed
Pucci F, Venneri MA, Biziato D, Nonis A, Moi D, Sica A, Di Serio C, Naldini L, De Palma M:
A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships.
Blood; 2009 Jul 23; 114(4) 901-14. doi:10.1182/blood-2009-01-200931
2009		 Abstract PubMed
Santiago-Raber ML, Amano H, Amano E, Baudino L, Otani M, Lin Q, Nimmerjahn F, Verbeek JS, Ravetch JV, Takasaki Y, Hirose S, Izui S:
Fcgamma receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice.
Arthritis Rheum.; 2009 Aug; 60(8) 2408-17. doi:10.1002/art.24787
2009		 Abstract PubMed
Jakubzick C, Tacke F, Ginhoux F, Wagers AJ, van Rooijen N, Mack M, Merad M, Randolph GJ:
Blood monocyte subsets differentially give rise to CD103+ and CD103- pulmonary dendritic cell populations.
J. Immunol.; 2008 Mar 01; 180(5) 3019-27
2008		 Abstract PubMed
Burke B, Ahmad R, Staples KJ, Snowden R, Kadioglu A, Frankenberger M, Hume DA, Ziegler-Heitbrock L:
Increased TNF expression in CD43++ murine blood monocytes.
Immunol. Lett.; 2008 Jun 30; 118(2) 142-7. doi:10.1016/j.imlet.2008.03.012
2008		 Abstract PubMed
Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ:
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions.
J. Exp. Med.; 2007 Nov 26; 204(12) 3037-47
2007		 Abstract PubMed
Varol C, Landsman L, Fogg DK, Greenshtein L, Gildor B, Margalit R, Kalchenko V, Geissmann F, Jung S:
Monocytes give rise to mucosal, but not splenic, conventional dendritic cells.
J. Exp. Med.; 2007 Jan 22; 204(1) 171-80
2007		 Abstract PubMed
Tacke F, Alvarez D, Kaplan TJ, Jakubzick C, Spanbroek R, Llodra J, Garin A, Liu J, Mack M, van Rooijen N, Lira SA, Habenicht AJ, Randolph GJ:
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques.
J. Clin. Invest.; 2007 Jan; 117(1) 185-94
2007		 Abstract PubMed
Landsman L, Varol C, Jung S:
Distinct differentiation potential of blood monocyte subsets in the lung.
J. Immunol.; 2007 Feb 15; 178(4) 2000-7
2007		 Abstract PubMed
Auffray C, Fogg D, Garfa M, Elain G, Join-Lambert O, Kayal S, Sarnacki S, Cumano A, Lauvau G, Geissmann F:
Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior.
Science; 2007 Aug 03; 317(5838) 666-70
2007		 Abstract PubMed
Serbina NV, Pamer EG:
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2.
Nat. Immunol.; 2006 Mar; 7(3) 311-7
2006		 Abstract PubMed
Tacke F, Randolph GJ:
Migratory fate and differentiation of blood monocyte subsets.
Immunobiology; 2006; 211(6-8) 609-18
2006		 Abstract PubMed
Nikolic T, Geutskens SB, van Rooijen N, Drexhage HA, Leenen PJ:
Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the nonobese diabetic mouse: a phagocyte depletion study.
Lab. Invest.; 2005 Apr; 85(4) 487-501
2005		 Abstract PubMed
Nikolic T, Bouma G, Drexhage HA, Leenen PJ:
Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro.
J. Leukoc. Biol.; 2005 Jul; 78(1) 70-9
2005		 Abstract PubMed
De Palma M, Venneri MA, Galli R, Sergi Sergi L, Politi LS, Sampaolesi M, Naldini L:
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.
Cancer Cell; 2005 Sep; 8(3) 211-26
2005		 Abstract PubMed
Mestas J, Hughes CC:
Of mice and not men: differences between mouse and human immunology.
J. Immunol.; 2004 Mar 01; 172(5) 2731-8
2004		 Abstract PubMed
Sunderkötter C, Nikolic T, Dillon MJ, Van Rooijen N, Stehling M, Drevets DA, Leenen PJ:
Subpopulations of mouse blood monocytes differ in maturation stage and inflammatory response.
J. Immunol.; 2004 Apr 01; 172(7) 4410-7
2004		 Abstract PubMed
Geissmann F, Jung S, Littman DR:
Blood monocytes consist of two principal subsets with distinct migratory properties.
Immunity; 2003 Jul; 19(1) 71-82
2003		 Abstract PubMed
Maus U, von Grote K, Kuziel WA, Mack M, Miller EJ, Cihak J, Stangassinger M, Maus R, Schlöndorff D, Seeger W, Lohmeyer J:
The role of CC chemokine receptor 2 in alveolar monocyte and neutrophil immigration in intact mice.
Am. J. Respir. Crit. Care Med.; 2002 Aug 01; 166(3) 268-73
2002		 Abstract PubMed
Palframan RT, Jung S, Cheng G, Weninger W, Luo Y, Dorf M, Littman DR, Rollins BJ, Zweerink H, Rot A, von Andrian UH:
Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues.
J. Exp. Med.; 2001 Nov 05; 194(9) 1361-73
2001		 Abstract PubMed